Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Songlin Chen
  • Guojie Zhang
  • Changwei Shao
  • Quanfei Huang
  • Geng Liu
  • Pei Zhang
  • Wentao Song
  • Na An
  • Domitille Chalopin
  • Jean-Nicolas Volff
  • Yunhan Hong
  • Qiye Li
  • Zhenxia Sha
  • Heling Zhou
  • Mingshu Xie
  • Qiulin Yu
  • Yang Liu
  • Hui Xiang
  • Na Wang
  • Kui Wu
  • Changgeng Yang
  • Qian Zhou
  • Xiaolin Liao
  • Linfeng Yang
  • Qiaomu Hu
  • Liang Meng
  • Lijun Jin
  • Yongsheng Tian
  • Jinmin Lian
  • Jingfeng Yang
  • Guidong Miao
  • Shanshan Liu
  • Zhuo Liang
  • Fang Yan
  • Yangzhen Li
  • Bin Sun
  • Hong Zhang
  • Jing Zhang
  • Ying Zhu
  • Min Du
  • Yongwei Zhao
  • Manfred Schartl
  • Qisheng Tang
  • Jun Wang

Detail(s)

Original languageEnglish
Pages (from-to)253-260
Journal / PublicationNature Genetics
Volume46
Issue number3
Publication statusPublished - Mar 2014
Externally publishedYes

Link(s)

Abstract

Genetic sex determination by W and Z chromosomes has developed independently in different groups of organisms. To better understand the evolution of sex chromosomes and the plasticity of sex-determination mechanisms, we sequenced the whole genomes of a male (ZZ) and a female (ZW) half-smooth tongue sole (Cynoglossus semilaevis). In addition to insights into adaptation to a benthic lifestyle, we find that the sex chromosomes of these fish are derived from the same ancestral vertebrate protochromosome as the avian W and Z chromosomes. Notably, the same gene on the Z chromosome, dmrt1, which is the male-determining gene in birds, showed convergent evolution of features that are compatible with a similar function in tongue sole. Comparison of the relatively young tongue sole sex chromosomes with those of mammals and birds identified events that occurred during the early phase of sex-chromosome evolution. Pertinent to the current debate about heterogametic sex-chromosome decay, we find that massive gene loss occurred in the wake of sex-chromosome 'birth'. © 2014 Nature America, Inc. © 2014 Nature America, Inc.

Research Area(s)

Bibliographic Note

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Citation Format(s)

Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle. / Chen, Songlin; Zhang, Guojie; Shao, Changwei et al.
In: Nature Genetics, Vol. 46, No. 3, 03.2014, p. 253-260.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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