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Wettability and biocompatibility of nitrogen-doped hydrogenated amorphous carbon films: Effect of nitrogen

  • P. Yang
  • , N. Huang
  • , Y. X. Leng
  • , Z. Q. Yao
  • , H. F. Zhou
  • , M. Maitz
  • , Y. Leng
  • , P. K. Chu

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Abstract

    Amorphous carbon films have been applied in biomedical fields as potential biocompatible materials with wettability that can be adjusted by doping with other elements, including F, Si, Ti, O and N. In this study, nitrogen-doped hydrogenated amorphous carbon (a-C:H:N) films were deposited by PIII-D using C2H2 + N2 gas mixtures. The biocompatibility and anti-thrombotic properties of the films were assessed in vitro. The surface morphology and surface wettability of the films were characterized using atomic force microscopy (AFM) and a contact angle method. The results show no cytotoxicity for all films, and films with appropriate nitrogen doping possess much better endothelial cell growth and anti-thrombotic properties. © 2005 Elsevier B.V. All rights reserved.
    Original languageEnglish
    Pages (from-to)22-25
    JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
    Volume242
    Issue number1-2
    DOIs
    Publication statusPublished - Jan 2006

    Research Keywords

    • Biocompatibility
    • Nitrogen-doped hydrogenated amorphous carbon (a-C:H:N)
    • Plasma immersion ion implantation-deposition (PIII-D)
    • Wettability

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