Wearable bio-adhesive metal detector array (BioMDA) for spinal implants

Jian Li; Shengxin Jia; Dengfeng Li; Lung Chow; Qiang Zhang; Yiyuan Yang; Xiao Bai; Qingao Qu; Yuyu Gao; Zhiyuan Li; Zongze Li; Rui Shi; Binbin Zhang; Ya Huang; Xinyu Pan; Yue Hu; Zhan Gao; Jingkun Zhou; WooYoung Park; Xingcan Huang; Hongwei Chu; Zhenlin Chen; Hu Li; Pengcheng Wu; Guangyao Zhao; Kuanming Yao; Muhamed Hadzipasic; Joshua D. Bernstock; Ganesh M. Shankar; Kewang Nan; Xinge Yu; Giovanni Traverso

doi:10.1038/s41467-024-51987-2

Wearable bio-adhesive metal detector array (BioMDA) for spinal implants

Jian Li, Shengxin Jia, Dengfeng Li, Lung Chow, Qiang Zhang, Yiyuan Yang, Xiao Bai, Qingao Qu, Yuyu Gao, Zhiyuan Li, Zongze Li, Rui Shi, Binbin Zhang, Ya Huang, Xinyu Pan, Yue Hu, Zhan Gao, Jingkun Zhou, WooYoung Park, Xingcan HuangHongwei Chu, Zhenlin Chen, Hu Li, Pengcheng Wu, Guangyao Zhao, Kuanming Yao, Muhamed Hadzipasic, Joshua D. Bernstock, Ganesh M. Shankar^*, Kewang Nan^*, Xinge Yu^*, Giovanni Traverso^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

7 Citations (Scopus)

33 Downloads (CityUHK Scholars)

Abstract

Dynamic tracking of spinal instrumentation could facilitate real-time evaluation of hardware integrity and in so doing alert patients/clinicians of potential failure(s). Critically, no method yet exists to continually monitor the integrity of spinal hardware and by proxy the process of spinal arthrodesis; as such hardware failures are often not appreciated until clinical symptoms manifest. Accordingly, herein, we report on the development and engineering of a bio-adhesive metal detector array (BioMDA), a potential wearable solution for real-time, non-invasive positional analyses of osseous implants within the spine. The electromagnetic coupling mechanism and intimate interfacial adhesion enable the precise sensing of the metallic implants position without the use of radiation. The customized decoupling models developed facilitate the precise determination of the horizontal and vertical positions of the implants with incredible levels of accuracy (e.g., <0.5 mm). These data support the potential use of BioMDA in real-time/dynamic postoperative monitoring of spinal implants. © The Author(s) 2024.

Original language	English
Article number	7800
Journal	Nature Communications
Volume	15
Online published	6 Sept 2024
DOIs	https://doi.org/10.1038/s41467-024-51987-2
Publication status	Published - 2024

Funding

This work was supported in part by: InnoHK Project on Project 2.2—AI-based 3D ultrasound imaging algorithm at Hong Kong Centre for Cerebro-Cardiovascular Health Engineering (COCHE), City University of Hong Kong (Grants No. 9667221, 924007 and 9680322), National Natural Science Foundation of China (Grants No. 62122002), Research Grants Council of the Hong Kong Special Administrative Region (Grant No. RFS2324-1S03), Shenzhen Science and Technology Innovation Commission (Grant No. SGDX20220530111401011), the Innovation and Technology Fund of Innovation and Technology Commission (Grant No. ITS/119/22), Karl Van Tassel (1925) Career Development Professorship and. The Department of Mechanical Engineering, MIT.

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This full text is made available under CC-BY 4.0. https://creativecommons.org/licenses/by/4.0/

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@article{d0c994b3cc794ff19229a99d96ea013e,

title = "Wearable bio-adhesive metal detector array (BioMDA) for spinal implants",

abstract = "Dynamic tracking of spinal instrumentation could facilitate real-time evaluation of hardware integrity and in so doing alert patients/clinicians of potential failure(s). Critically, no method yet exists to continually monitor the integrity of spinal hardware and by proxy the process of spinal arthrodesis; as such hardware failures are often not appreciated until clinical symptoms manifest. Accordingly, herein, we report on the development and engineering of a bio-adhesive metal detector array (BioMDA), a potential wearable solution for real-time, non-invasive positional analyses of osseous implants within the spine. The electromagnetic coupling mechanism and intimate interfacial adhesion enable the precise sensing of the metallic implants position without the use of radiation. The customized decoupling models developed facilitate the precise determination of the horizontal and vertical positions of the implants with incredible levels of accuracy (e.g., <0.5 mm). These data support the potential use of BioMDA in real-time/dynamic postoperative monitoring of spinal implants. {\textcopyright} The Author(s) 2024.",

author = "Jian Li and Shengxin Jia and Dengfeng Li and Lung Chow and Qiang Zhang and Yiyuan Yang and Xiao Bai and Qingao Qu and Yuyu Gao and Zhiyuan Li and Zongze Li and Rui Shi and Binbin Zhang and Ya Huang and Xinyu Pan and Yue Hu and Zhan Gao and Jingkun Zhou and WooYoung Park and Xingcan Huang and Hongwei Chu and Zhenlin Chen and Hu Li and Pengcheng Wu and Guangyao Zhao and Kuanming Yao and Muhamed Hadzipasic and Bernstock, {Joshua D.} and Shankar, {Ganesh M.} and Kewang Nan and Xinge Yu and Giovanni Traverso",

year = "2024",

doi = "10.1038/s41467-024-51987-2",

language = "English",

volume = "15",

journal = "Nature Communications",

issn = "2041-1723",

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Li, J, Jia, S, Li, D , Chow, L, Zhang, Q, Yang, Y, Bai, X, Qu, Q, Gao, Y, Li, Z, Li, Z, Shi, R, Zhang, B, Huang, Y, Pan, X, Hu, Y, Gao, Z , Zhou, J , Park, W , Huang, X, Chu, H, Chen, Z, Li, H, Wu, P , Zhao, G , Yao, K, Hadzipasic, M, Bernstock, JD, Shankar, GM, Nan, K, Yu, X & Traverso, G 2024, 'Wearable bio-adhesive metal detector array (BioMDA) for spinal implants', Nature Communications, vol. 15, 7800. https://doi.org/10.1038/s41467-024-51987-2

TY - JOUR

T1 - Wearable bio-adhesive metal detector array (BioMDA) for spinal implants

AU - Li, Jian

AU - Jia, Shengxin

AU - Li, Dengfeng

AU - Chow, Lung

AU - Zhang, Qiang

AU - Yang, Yiyuan

AU - Bai, Xiao

AU - Qu, Qingao

AU - Gao, Yuyu

AU - Li, Zhiyuan

AU - Li, Zongze

AU - Shi, Rui

AU - Zhang, Binbin

AU - Huang, Ya

AU - Pan, Xinyu

AU - Hu, Yue

AU - Gao, Zhan

AU - Zhou, Jingkun

AU - Park, WooYoung

AU - Huang, Xingcan

AU - Chu, Hongwei

AU - Chen, Zhenlin

AU - Li, Hu

AU - Wu, Pengcheng

AU - Zhao, Guangyao

AU - Yao, Kuanming

AU - Hadzipasic, Muhamed

AU - Bernstock, Joshua D.

AU - Shankar, Ganesh M.

AU - Nan, Kewang

AU - Yu, Xinge

AU - Traverso, Giovanni

PY - 2024

Y1 - 2024

N2 - Dynamic tracking of spinal instrumentation could facilitate real-time evaluation of hardware integrity and in so doing alert patients/clinicians of potential failure(s). Critically, no method yet exists to continually monitor the integrity of spinal hardware and by proxy the process of spinal arthrodesis; as such hardware failures are often not appreciated until clinical symptoms manifest. Accordingly, herein, we report on the development and engineering of a bio-adhesive metal detector array (BioMDA), a potential wearable solution for real-time, non-invasive positional analyses of osseous implants within the spine. The electromagnetic coupling mechanism and intimate interfacial adhesion enable the precise sensing of the metallic implants position without the use of radiation. The customized decoupling models developed facilitate the precise determination of the horizontal and vertical positions of the implants with incredible levels of accuracy (e.g., <0.5 mm). These data support the potential use of BioMDA in real-time/dynamic postoperative monitoring of spinal implants. © The Author(s) 2024.

AB - Dynamic tracking of spinal instrumentation could facilitate real-time evaluation of hardware integrity and in so doing alert patients/clinicians of potential failure(s). Critically, no method yet exists to continually monitor the integrity of spinal hardware and by proxy the process of spinal arthrodesis; as such hardware failures are often not appreciated until clinical symptoms manifest. Accordingly, herein, we report on the development and engineering of a bio-adhesive metal detector array (BioMDA), a potential wearable solution for real-time, non-invasive positional analyses of osseous implants within the spine. The electromagnetic coupling mechanism and intimate interfacial adhesion enable the precise sensing of the metallic implants position without the use of radiation. The customized decoupling models developed facilitate the precise determination of the horizontal and vertical positions of the implants with incredible levels of accuracy (e.g., <0.5 mm). These data support the potential use of BioMDA in real-time/dynamic postoperative monitoring of spinal implants. © The Author(s) 2024.

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U2 - 10.1038/s41467-024-51987-2

DO - 10.1038/s41467-024-51987-2

M3 - RGC 21 - Publication in refereed journal

C2 - 39242511

SN - 2041-1723

VL - 15

JO - Nature Communications

JF - Nature Communications

M1 - 7800

ER -

Wearable bio-adhesive metal detector array (BioMDA) for spinal implants

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RFS: Skin-Integrated and Multi-functional Closed Loop Human Machine Interface: Sensing, Actuation, and System Integration

ITF: An Intelligent Haptic Glove for Metaverse

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Wearable bio-adhesive metal detector array (BioMDA) for spinal implants

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RFS: Skin-Integrated and Multi-functional Closed Loop Human Machine Interface: Sensing, Actuation, and System Integration

ITF: An Intelligent Haptic Glove for Metaverse

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