TY - GEN
T1 - Virus infectivity detection by effective refractive index using optofluidic imaging
AU - Liu, P. Y.
AU - Chin, L. K.
AU - Ser, W.
AU - Ayi, T. C.
AU - Yap, P. H.
AU - Bourouina, T.
AU - Leprince-Wang, Y.
N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].
PY - 2014
Y1 - 2014
N2 - This paper presents an optofluidic imaging system to detect influenza virus infection via co-culture of Madin Darby Canine Kidney (MDCK) cells. Influenza flu virus is a serious threat that can cause contagious infections in people in epidemic proportions. Hence, it is crucial to accurately detect and understand the morphological changes that occur in the cells when infected by the influenza virus. Recently, researchers are investigating the biophysical properties of cells and correlating them to biomedical conditions. For example, a decrease in refractive index (RI) is observed in bacterial infected cells [1]. In this paper, an optofluidic imaging system is developed to observe the change of RI in virus infected cells based on scattering signature.
AB - This paper presents an optofluidic imaging system to detect influenza virus infection via co-culture of Madin Darby Canine Kidney (MDCK) cells. Influenza flu virus is a serious threat that can cause contagious infections in people in epidemic proportions. Hence, it is crucial to accurately detect and understand the morphological changes that occur in the cells when infected by the influenza virus. Recently, researchers are investigating the biophysical properties of cells and correlating them to biomedical conditions. For example, a decrease in refractive index (RI) is observed in bacterial infected cells [1]. In this paper, an optofluidic imaging system is developed to observe the change of RI in virus infected cells based on scattering signature.
KW - Optofluidics
KW - Scattering signature
KW - Virus infectivity
UR - http://www.scopus.com/inward/record.url?scp=84941696036&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84941696036&origin=recordpage
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 9780979806476
T3 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
SP - 2309
EP - 2311
BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PB - Chemical and Biological Microsystems Society
T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Y2 - 26 October 2014 through 30 October 2014
ER -
