Video-rate photoacoustic microscopy of micro-vasculatures

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

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Author(s)

  • Lidai Wang
  • Konstantin Maslov
  • Wenxin Xing
  • Alejandro Garcia-Uribe
  • Lihong V. Wang

Detail(s)

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8581
Publication statusPublished - 2013
Externally publishedYes

Publication series

Name
Volume8581
ISSN (Print)1605-7422

Conference

TitlePhotons Plus Ultrasound: Imaging and Sensing 2013
PlaceUnited States
CitySan Francisco, CA
Period3 - 5 February 2013

Link(s)

DOI

DOI
Check@CityULib
Link to Scopus https://www.scopus.com/record/display.uri?eid=2-s2.0-84878026475&origin=recordpage
Permanent Link https://scholars.cityu.edu.hk/en/publications/publication(33282393-3957-42d1-9bb3-046ccf6b01ad).html

Abstract

We report the development of photoacoustic microscopy capable of video-rate high-resolution in-vivo imaging in deep tissue. A lightweight photoacoustic probe is made of a single-element broadband ultrasound transducer, a compact photoacoustic beam combiner, and a bright-field light delivery system. Focused broadband ultrasound detection provides a 44-μm lateral resolution and a 28-μm axial resolution. A multimode optical fiber is used to deliver laser pulses. The bright-field light delivery system can effectively improve the illumination efficiency. The photoacoustic probe weighs less than 40 grams and is mounted on a voice-coil scanner to acquire 40 cross-sectional images per second over several-mm range. The fast speed can effectively improve imaging throughput, reduce motion artifacts, and enable the visualization of highly dynamic biomedical processes. High-resolution micro-vascular imaging is successfully demonstrated. © 2013 Copyright SPIE.

Research Area(s)

  • cardiovascular imaging, deep imaging, fast scanning speed, Photoacoustic imaging

Fingerprint

Publication fingerprints text

100
High Resolution Physics
100
Rate Video Engineering
100
Light Field Engineering
100
Microvessel Medicine and Dentistry
100
Photoacoustic Micro... Medicine and Dentistry
50
Transducer Physics
50
Laser Pulse Physics
50
Angiography Physics
50
Glass Fiber Physics
50
Multimode Engineering
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Citation Format(s)

[ RIS ] [ BibTeX ]
Video-rate photoacoustic microscopy of micro-vasculatures. / Wang, Lidai; Maslov, Konstantin; Xing, Wenxin et al.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8581 2013. 85811T.

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review