Vascular endothelial cell compatibility of superhard ternary Ti–Si–N coatings with different Si contents

Ming Zhang; Shengli Ma; Kewei Xu; Paul K. Chu

doi:10.1016/j.vacuum.2014.02.009

Vascular endothelial cell compatibility of superhard ternary Ti–Si–N coatings with different Si contents

Ming Zhang, Shengli Ma, Kewei Xu, Paul K. Chu^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

5 Citations (Scopus)

Abstract

Superhard ternary Ti-Si-N coatings with different Si atomic concentrations are deposited on titanium alloy substrates by arc-enhanced magnetron sputtering (AEMS) and the vascular endothelial cell compatibility is studied. In vitro studies show that the surface hydrophilicity and hemolysis are about the same as those of the titanium alloy control and platelet adhesion and protein adsorption tests suggest a close relationship between the surface energy and blood compatibility. Endothelial cells cultures reveal better proliferation and anti-platelet adhesion on the coatings compared to the titanium alloy control and the Ti-Si-N coating with 20 at% Si exhibits excellent endothelialization. © 2014 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	53-63
Journal	Vacuum
Volume	106
Online published	18 Mar 2014
DOIs	https://doi.org/10.1016/j.vacuum.2014.02.009
Publication status	Published - Aug 2014

Research Keywords

Blood compatibility
Endothelialization
Ti-Si-N coatings

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title = "Vascular endothelial cell compatibility of superhard ternary Ti–Si–N coatings with different Si contents",

abstract = "Superhard ternary Ti-Si-N coatings with different Si atomic concentrations are deposited on titanium alloy substrates by arc-enhanced magnetron sputtering (AEMS) and the vascular endothelial cell compatibility is studied. In vitro studies show that the surface hydrophilicity and hemolysis are about the same as those of the titanium alloy control and platelet adhesion and protein adsorption tests suggest a close relationship between the surface energy and blood compatibility. Endothelial cells cultures reveal better proliferation and anti-platelet adhesion on the coatings compared to the titanium alloy control and the Ti-Si-N coating with 20 at% Si exhibits excellent endothelialization. {\textcopyright} 2014 Elsevier B.V. All rights reserved.",

keywords = "Blood compatibility, Endothelialization, Ti-Si-N coatings",

author = "Ming Zhang and Shengli Ma and Kewei Xu and Chu, {Paul K.}",

year = "2014",

month = aug,

doi = "10.1016/j.vacuum.2014.02.009",

language = "English",

volume = "106",

pages = "53--63",

journal = "Vacuum",

issn = "0042-207X",

publisher = "Elsevier Ltd.",

}

TY - JOUR

T1 - Vascular endothelial cell compatibility of superhard ternary Ti–Si–N coatings with different Si contents

AU - Zhang, Ming

AU - Ma, Shengli

AU - Xu, Kewei

AU - Chu, Paul K.

PY - 2014/8

Y1 - 2014/8

N2 - Superhard ternary Ti-Si-N coatings with different Si atomic concentrations are deposited on titanium alloy substrates by arc-enhanced magnetron sputtering (AEMS) and the vascular endothelial cell compatibility is studied. In vitro studies show that the surface hydrophilicity and hemolysis are about the same as those of the titanium alloy control and platelet adhesion and protein adsorption tests suggest a close relationship between the surface energy and blood compatibility. Endothelial cells cultures reveal better proliferation and anti-platelet adhesion on the coatings compared to the titanium alloy control and the Ti-Si-N coating with 20 at% Si exhibits excellent endothelialization. © 2014 Elsevier B.V. All rights reserved.

AB - Superhard ternary Ti-Si-N coatings with different Si atomic concentrations are deposited on titanium alloy substrates by arc-enhanced magnetron sputtering (AEMS) and the vascular endothelial cell compatibility is studied. In vitro studies show that the surface hydrophilicity and hemolysis are about the same as those of the titanium alloy control and platelet adhesion and protein adsorption tests suggest a close relationship between the surface energy and blood compatibility. Endothelial cells cultures reveal better proliferation and anti-platelet adhesion on the coatings compared to the titanium alloy control and the Ti-Si-N coating with 20 at% Si exhibits excellent endothelialization. © 2014 Elsevier B.V. All rights reserved.

KW - Blood compatibility

KW - Endothelialization

KW - Ti-Si-N coatings

UR - http://www.scopus.com/inward/record.url?scp=84897494676&partnerID=8YFLogxK

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84897494676&origin=recordpage

U2 - 10.1016/j.vacuum.2014.02.009

DO - 10.1016/j.vacuum.2014.02.009

M3 - RGC 21 - Publication in refereed journal

SN - 0042-207X

VL - 106

SP - 53

EP - 63

JO - Vacuum

JF - Vacuum

ER -

Vascular endothelial cell compatibility of superhard ternary Ti–Si–N coatings with different Si contents

Abstract

Research Keywords

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