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Upconverting nanoparticles for cellular imaging

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

Abstract

Fluorescent labels that are excited by the near infrared (NIR) radiation are advantageous because these give rise to minimal autofluorescence because of lack of efficient endogenous absorbers in the NIR spectral range [1-3], and results in very high signal to background ratios. Furthermore, photo-damage to cells and tissues is also greatly reduced because NIR is generally harmless to biomolecules in low doses. In this report we present the use of ultrafine, pure cubic silica coated NaYF4 nanocrystals co-doped with lanthanide ions ions Yb3+ and Er3+. To the best of our knowledge these represent the first report of the use of sub-40 nm upconversion nanoparticles in biomedical imaging.
Original languageEnglish
Title of host publicationTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Pages535-538
Volume2
Publication statusPublished - 2008
Externally publishedYes
Event2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008 - Quebec City, QC, United States
Duration: 1 Jun 20085 Jun 2008

Publication series

NameTechnical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Volume2

Conference

Conference2008 NSTI Nanotechnology Conference and Trade Show, NSTI Nanotech 2008 Joint Meeting, Nanotechnology 2008
PlaceUnited States
CityQuebec City, QC
Period1/06/085/06/08

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Research Keywords

  • Imaging
  • Lanthanides
  • Nanoparticles
  • Upconversion

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