Unsymmetrical β-cyclodextrin-conjugated silicon(iv) phthalocyanines as highly potent photosensitisers for photodynamic therapy
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 9657-9659 |
Journal / Publication | Chemical Communications |
Volume | 47 |
Issue number | 34 |
Publication status | Published - 14 Sept 2011 |
Externally published | Yes |
Link(s)
Abstract
A series of unsymmetrical silicon(iv) phthalocyanines with a permethylated β-cyclodextrin unit and a sugar or a diamino moiety as the axial substituents have been prepared. These compounds are highly photocytotoxic with IC 50 values as low as 21 nM, which is ca. sevenfold lower than those of the symmetrical bis(cyclodextrin) analogue. © The Royal Society of Chemistry 2011.
Research Area(s)
Citation Format(s)
Unsymmetrical β-cyclodextrin-conjugated silicon(iv) phthalocyanines as highly potent photosensitisers for photodynamic therapy. / Lau, Janet T. F.; Lo, Pui-Chi; Tsang, Yee-Man et al.
In: Chemical Communications, Vol. 47, No. 34, 14.09.2011, p. 9657-9659.
In: Chemical Communications, Vol. 47, No. 34, 14.09.2011, p. 9657-9659.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review