Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Ying Ding
  • Weimin Liu
  • Jiasheng Wu
  • Xiuli Zheng
  • Jiechao Ge
  • Haohui Ren
  • Pengfei Wang

Detail(s)

Original languageEnglish
Pages (from-to)1221–1224
Journal / PublicationChemistry - An Asian Journal
Volume16
Issue number10
Online published21 Apr 2021
Publication statusPublished - 17 May 2021

Abstract

Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.

Research Area(s)

  • Hypocrellin B, Peroxyoxalate, Self-exciting photodynamic therapy, Ultrasound-enhanced chemiluminescence

Citation Format(s)

Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B. / Ding, Ying; Liu, Weimin; Wu, Jiasheng; Zheng, Xiuli; Ge, Jiechao; Ren, Haohui; Zhang, Wenjun; Lee, Chun-Sing; Wang, Pengfei.

In: Chemistry - An Asian Journal, Vol. 16, No. 10, 17.05.2021, p. 1221–1224.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review