Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B

Ying Ding; Weimin Liu; Jiasheng Wu; Xiuli Zheng; Jiechao Ge; Haohui Ren; Wenjun Zhang; Chun-Sing Lee; Pengfei Wang

doi:10.1002/asia.202100205

Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B

Ying Ding
, Weimin Liu^*
, Jiasheng Wu
, Xiuli Zheng
, Jiechao Ge
, Haohui Ren
, Wenjun Zhang
, Chun-Sing Lee
, Pengfei Wang^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

8 Citations (Scopus)

Abstract

Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.

Original language	English
Pages (from-to)	1221–1224
Journal	Chemistry - An Asian Journal
Volume	16
Issue number	10
Online published	21 Apr 2021
DOIs	https://doi.org/10.1002/asia.202100205
Publication status	Published - 17 May 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Keywords

Hypocrellin B
Peroxyoxalate
Self-exciting photodynamic therapy
Ultrasound-enhanced chemiluminescence

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10.1002/asia.202100205

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title = "Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B",

abstract = "Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.",

keywords = "Hypocrellin B, Peroxyoxalate, Self-exciting photodynamic therapy, Ultrasound-enhanced chemiluminescence",

author = "Ying Ding and Weimin Liu and Jiasheng Wu and Xiuli Zheng and Jiechao Ge and Haohui Ren and Wenjun Zhang and Chun-Sing Lee and Pengfei Wang",

year = "2021",

month = may,

day = "17",

doi = "10.1002/asia.202100205",

language = "English",

volume = "16",

pages = "1221–1224",

journal = "Chemistry - An Asian Journal",

issn = "1861-4728",

publisher = "John Wiley \& Sons",

number = "10",

}

TY - JOUR

T1 - Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B

AU - Ding, Ying

AU - Liu, Weimin

AU - Wu, Jiasheng

AU - Zheng, Xiuli

AU - Ge, Jiechao

AU - Ren, Haohui

AU - Zhang, Wenjun

AU - Lee, Chun-Sing

AU - Wang, Pengfei

PY - 2021/5/17

Y1 - 2021/5/17

N2 - Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.

AB - Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.

KW - Hypocrellin B

KW - Peroxyoxalate

KW - Self-exciting photodynamic therapy

KW - Ultrasound-enhanced chemiluminescence

UR - https://www.scopus.com/pages/publications/85104643216

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85104643216&origin=recordpage

U2 - 10.1002/asia.202100205

DO - 10.1002/asia.202100205

M3 - RGC 21 - Publication in refereed journal

SN - 1861-4728

VL - 16

SP - 1221

EP - 1224

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

IS - 10

ER -

Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B

Abstract

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