Type II collagen scaffolds for tissue engineering

Xu Hu; Zhonglian Wu; Zhen Zhang; Hang Yao; Dong-An Wang

doi:10.1038/s43246-024-00598-x

Type II collagen scaffolds for tissue engineering

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

1 Scopus Citations

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Author(s)

Xu Hu
Zhonglian Wu
Zhen Zhang
Hang Yao
Dong-An Wang

Related Research Unit(s)

Department of Biomedical Engineering

Detail(s)

Original language	English
Article number	149
Journal / Publication	Communications Materials
Volume	5
Online published	10 Aug 2024
Publication status	Published - 2024

Link(s)

DOI	DOI https://doi.org/10.1038/s43246-024-00598-x Final Published version
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Attachment(s)	Documents 237803703.pdf Final Published version, 3.59 MB, PDF Publisher's Copyright Statement This full text is made available under CC-BY 4.0. https://creativecommons.org/licenses/by/4.0/
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-85201185265&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(628b789c-ddb3-43ae-b9a4-e81a30c7e526).html

Abstract

Type II collagen (CII), a key component of cartilaginous tissues, offers an attractive option for fabricating biomimetic scaffolds that provide mechanical support and biochemical signals to facilitate cell adhesion, proliferation, and differentiation. Advances in fabrication technologies have enabled the creation of intricate and multicellular CII-based scaffolds that more accurately replicate the natural structure of tissues. Here, we review the application of CII in tissue engineering and highlight its crucial contributions to the regeneration of hyaline cartilage and intervertebral discs. Additionally, we discuss the versatile roles of CII in other biomedical applications, including disease modeling, bone regeneration, and the development of artificial immune organs. © The Author(s) 2024.