Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform

Chi Lok Wong; Ho Pui Ho; Kin Fong Lei; Wen Jung Li; Kwok Sum Chan; Wing Cheung Law; Shu Yuen Wu; Siu Kai Kong; Chinlon Lin

doi:10.1109/EDSSC.2005.1635374

Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform

Chi Lok Wong
, Ho Pui Ho
, Kin Fong Lei
, Wen Jung Li
, Kwok Sum Chan
, Wing Cheung Law
, Shu Yuen Wu
, Siu Kai Kong
, Chinlon Lin

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

2 Citations (Scopus)

Abstract

The integration between 2D SPR differential phase imaging sensor and microfluidic flow circuit is presented. It provides the advantages of high throughput, high sensitivity and label free detection to meet the present needs in biomechanical market. The differential phase scheme between p- and s- polarization enable elimination of all common-path phase noise while keeping the phase change caused by SPR effect. System sensitivity of the detection sensitivity of our setup is 0.44μg /ml is obtained for salt / water mixture sensing. BSA antigen and antibody binding reaction detection is further demonstrated. The system shows the capability of simultaneous detection for both specific and non-specific binding reactions in a micro-chamber array. ©2005 IEEE.

Original language	English
Title of host publication	2005 IEEE Conference on Electron Devices and Solid-State Circuits, EDSSC
Pages	709-712
DOIs	https://doi.org/10.1109/EDSSC.2005.1635374
Publication status	Published - 2006
Event	2005 IEEE Conference on Electron Devices and Solid-State Circuits (EDSSC 2005) - New World Renaissance Hotel, Hong Kong, China Duration: 19 Dec 2005 → 21 Dec 2005

Conference

Conference	2005 IEEE Conference on Electron Devices and Solid-State Circuits (EDSSC 2005)
Place	China
City	Hong Kong
Period	19/12/05 → 21/12/05

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Wong, C. L., Ho, H. P., Lei, K. F., Li, W. J., Chan, K. S., Law, W. C., Wu, S. Y., Kong, S. K., & Lin, C. (2006). Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform. In 2005 IEEE Conference on Electron Devices and Solid-State Circuits, EDSSC (pp. 709-712). Article 1635374 https://doi.org/10.1109/EDSSC.2005.1635374

@inproceedings{edc9fd4cc0b64ceea072d762110717db,

title = "Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform",

abstract = "The integration between 2D SPR differential phase imaging sensor and microfluidic flow circuit is presented. It provides the advantages of high throughput, high sensitivity and label free detection to meet the present needs in biomechanical market. The differential phase scheme between p- and s- polarization enable elimination of all common-path phase noise while keeping the phase change caused by SPR effect. System sensitivity of the detection sensitivity of our setup is 0.44μg /ml is obtained for salt / water mixture sensing. BSA antigen and antibody binding reaction detection is further demonstrated. The system shows the capability of simultaneous detection for both specific and non-specific binding reactions in a micro-chamber array. {\textcopyright}2005 IEEE.",

author = "Wong, \{Chi Lok\} and Ho, \{Ho Pui\} and Lei, \{Kin Fong\} and Li, \{Wen Jung\} and Chan, \{Kwok Sum\} and Law, \{Wing Cheung\} and Wu, \{Shu Yuen\} and Kong, \{Siu Kai\} and Chinlon Lin",

year = "2006",

doi = "10.1109/EDSSC.2005.1635374",

language = "English",

isbn = "0780393392",

pages = "709--712",

booktitle = "2005 IEEE Conference on Electron Devices and Solid-State Circuits, EDSSC",

note = "2005 IEEE Conference on Electron Devices and Solid-State Circuits (EDSSC 2005) ; Conference date: 19-12-2005 Through 21-12-2005",

}

Wong, CL, Ho, HP, Lei, KF, Li, WJ , Chan, KS, Law, WC, Wu, SY, Kong, SK & Lin, C 2006, Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform. in 2005 IEEE Conference on Electron Devices and Solid-State Circuits, EDSSC., 1635374, pp. 709-712, 2005 IEEE Conference on Electron Devices and Solid-State Circuits (EDSSC 2005), Hong Kong, China, 19/12/05. https://doi.org/10.1109/EDSSC.2005.1635374

Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform. / Wong, Chi Lok; Ho, Ho Pui; Lei, Kin Fong et al.
2005 IEEE Conference on Electron Devices and Solid-State Circuits, EDSSC. 2006. p. 709-712 1635374.

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform

AU - Wong, Chi Lok

AU - Ho, Ho Pui

AU - Lei, Kin Fong

AU - Li, Wen Jung

AU - Chan, Kwok Sum

AU - Law, Wing Cheung

AU - Wu, Shu Yuen

AU - Kong, Siu Kai

AU - Lin, Chinlon

PY - 2006

Y1 - 2006

N2 - The integration between 2D SPR differential phase imaging sensor and microfluidic flow circuit is presented. It provides the advantages of high throughput, high sensitivity and label free detection to meet the present needs in biomechanical market. The differential phase scheme between p- and s- polarization enable elimination of all common-path phase noise while keeping the phase change caused by SPR effect. System sensitivity of the detection sensitivity of our setup is 0.44μg /ml is obtained for salt / water mixture sensing. BSA antigen and antibody binding reaction detection is further demonstrated. The system shows the capability of simultaneous detection for both specific and non-specific binding reactions in a micro-chamber array. ©2005 IEEE.

AB - The integration between 2D SPR differential phase imaging sensor and microfluidic flow circuit is presented. It provides the advantages of high throughput, high sensitivity and label free detection to meet the present needs in biomechanical market. The differential phase scheme between p- and s- polarization enable elimination of all common-path phase noise while keeping the phase change caused by SPR effect. System sensitivity of the detection sensitivity of our setup is 0.44μg /ml is obtained for salt / water mixture sensing. BSA antigen and antibody binding reaction detection is further demonstrated. The system shows the capability of simultaneous detection for both specific and non-specific binding reactions in a micro-chamber array. ©2005 IEEE.

UR - https://www.scopus.com/pages/publications/43549087170

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-43549087170&origin=recordpage

U2 - 10.1109/EDSSC.2005.1635374

DO - 10.1109/EDSSC.2005.1635374

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 0780393392

SN - 9780780393394

SP - 709

EP - 712

BT - 2005 IEEE Conference on Electron Devices and Solid-State Circuits, EDSSC

T2 - 2005 IEEE Conference on Electron Devices and Solid-State Circuits (EDSSC 2005)

Y2 - 19 December 2005 through 21 December 2005

ER -

Two dimensional phase sensitive surface plasmon resonance biosensor array using microfluidic flow circuit platform

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