Tuning the organelle specificity and cytotoxicity of iridium(III) photosensitisers for enhanced phototheranostic applications

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

3 Scopus Citations
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Detail(s)

Original languageEnglish
Pages (from-to)12008-12011
Journal / PublicationChemical Communications
Volume57
Issue number90
Online published5 Oct 2021
Publication statusPublished - 21 Nov 2021

Abstract

Luminescent cyclometallated iridium(III) complexes with a polyhedral oligomeric silsesquioxane (POSS) unit were designed as efficient theranostic agents that displayed tuneable organelle-targeting properties, minimal dark cytotoxicity and substantial photocytotoxicity even under hypoxic conditions.

Research Area(s)

  • SINGLET OXYGEN, COMPLEXES, GENERATION

Citation Format(s)

Tuning the organelle specificity and cytotoxicity of iridium(III) photosensitisers for enhanced phototheranostic applications. / Zhu, Jing-Hui; Xu, Guang-Xi; Shum, Justin; Lee, Lawrence Cho-Cheung; Lo, Kenneth Kam-Wing.

In: Chemical Communications, Vol. 57, No. 90, 21.11.2021, p. 12008-12011.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review