Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes

Hamideh Sharifi Noghabi; Adrian J.T. Teo; Say Hwa Tan; Nam-Trung Nguyen; Paul C.H. Li

Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes

Hamideh Sharifi Noghabi, Adrian J.T. Teo, Say Hwa Tan, Nam-Trung Nguyen, Paul C.H. Li^*

^*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

Single-cell measurement has been achieved using a microfluidic dielectrophoresis (DEP) chip designed to combine DEP with same-single-cell analysis (SASCA). The DEP electrodes in the chip used to be fabricated by metal layers patterned on a glass bottom to be bonded to a top glass plate consisting of channels, chambers and solution reservoirs. In this work, we created DEP chip made of a top PDMS slab bonded to an unpatterned glass bottom, in which the electrodes were self-aligned by filling liquid metal into guiding channels.

Original language	English
Title of host publication	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Publisher	Chemical and Biological Microsystems Society
Pages	2466-2467
Volume	4
ISBN (Print)	9781510897571
Publication status	Published - 2018
Externally published	Yes
Event	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018) - Kaohsiung Exhibition Center, Kaohsiung, Taiwan, China Duration: 11 Nov 2018 → 15 Nov 2018 https://cbmsociety.org/microtas/microtas2018/ https://cbmsociety.org/wp-content/uploads/2018/11/uTAS-2018-FInal-Program-WEB.pdf https://archive.cbmsociety.org/utas/uTAS2018.zip

Publication series

Name	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume	4

Conference

Conference	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018)
Abbreviated title	μTAS2018
Place	Taiwan, China
City	Kaohsiung
Period	11/11/18 → 15/11/18
Internet address	https://cbmsociety.org/microtas/microtas2018/ https://cbmsociety.org/wp-content/uploads/2018/11/uTAS-2018-FInal-Program-WEB.pdf https://archive.cbmsociety.org/utas/uTAS2018.zip

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Research Keywords

Cell trapping
DEP
Drug accumulation measurement
Liquid metal
Yeast or cancer cell

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Noghabi, H. S., Teo, A. J. T., Tan, S. H., Nguyen, N.-T., & Li, P. C. H. (2018). Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes. In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 (Vol. 4, pp. 2466-2467). (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; Vol. 4). Chemical and Biological Microsystems Society.

Noghabi, Hamideh Sharifi ; Teo, Adrian J.T. ; Tan, Say Hwa et al. / Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Vol. 4 Chemical and Biological Microsystems Society, 2018. pp. 2466-2467 (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018).

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abstract = "Single-cell measurement has been achieved using a microfluidic dielectrophoresis (DEP) chip designed to combine DEP with same-single-cell analysis (SASCA). The DEP electrodes in the chip used to be fabricated by metal layers patterned on a glass bottom to be bonded to a top glass plate consisting of channels, chambers and solution reservoirs. In this work, we created DEP chip made of a top PDMS slab bonded to an unpatterned glass bottom, in which the electrodes were self-aligned by filling liquid metal into guiding channels.",

keywords = "Cell trapping, DEP, Drug accumulation measurement, Liquid metal, Yeast or cancer cell, Cell trapping, DEP, Drug accumulation measurement, Liquid metal, Yeast or cancer cell, Cell trapping, DEP, Drug accumulation measurement, Liquid metal, Yeast or cancer cell",

author = "Noghabi, {Hamideh Sharifi} and Teo, {Adrian J.T.} and Tan, {Say Hwa} and Nam-Trung Nguyen and Li, {Paul C.H.}",

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Noghabi, HS, Teo, AJT, Tan, SH, Nguyen, N-T & Li, PCH 2018, Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes. in 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. vol. 4, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, vol. 4, Chemical and Biological Microsystems Society, pp. 2466-2467, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan, China, 11/11/18.

Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes. / Noghabi, Hamideh Sharifi; Teo, Adrian J.T.; Tan, Say Hwa et al.
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Vol. 4 Chemical and Biological Microsystems Society, 2018. p. 2466-2467 (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; Vol. 4).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes

AU - Noghabi, Hamideh Sharifi

AU - Teo, Adrian J.T.

AU - Tan, Say Hwa

AU - Nguyen, Nam-Trung

AU - Li, Paul C.H.

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2018

Y1 - 2018

N2 - Single-cell measurement has been achieved using a microfluidic dielectrophoresis (DEP) chip designed to combine DEP with same-single-cell analysis (SASCA). The DEP electrodes in the chip used to be fabricated by metal layers patterned on a glass bottom to be bonded to a top glass plate consisting of channels, chambers and solution reservoirs. In this work, we created DEP chip made of a top PDMS slab bonded to an unpatterned glass bottom, in which the electrodes were self-aligned by filling liquid metal into guiding channels.

AB - Single-cell measurement has been achieved using a microfluidic dielectrophoresis (DEP) chip designed to combine DEP with same-single-cell analysis (SASCA). The DEP electrodes in the chip used to be fabricated by metal layers patterned on a glass bottom to be bonded to a top glass plate consisting of channels, chambers and solution reservoirs. In this work, we created DEP chip made of a top PDMS slab bonded to an unpatterned glass bottom, in which the electrodes were self-aligned by filling liquid metal into guiding channels.

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KW - DEP

KW - Drug accumulation measurement

KW - Liquid metal

KW - Yeast or cancer cell

KW - Cell trapping

KW - DEP

KW - Drug accumulation measurement

KW - Liquid metal

KW - Yeast or cancer cell

KW - Cell trapping

KW - DEP

KW - Drug accumulation measurement

KW - Liquid metal

KW - Yeast or cancer cell

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M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 9781510897571

VL - 4

T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018

SP - 2466

EP - 2467

BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018

PB - Chemical and Biological Microsystems Society

T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018)

Y2 - 11 November 2018 through 15 November 2018

ER -

Noghabi HS, Teo AJT, Tan SH, Nguyen NT, Li PCH. Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes. In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Vol. 4. Chemical and Biological Microsystems Society. 2018. p. 2466-2467. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018).

Trapping and measurement of biological cells using a microfluidic chip with self-aligned dielectrophoresis (DEP) electrodes

Abstract

Publication series

Conference

Bibliographical note

Research Keywords

UN SDGs

Other Access Options

Permanent Link

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