Thin, soft, skin-integrated electronics for real-time and wireless detection of uric acid in sweat

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)406–419
Number of pages14
Journal / PublicationInternational Journal of Smart and Nano Materials
Volume14
Issue number4
Online published24 Jul 2023
Publication statusPublished - 2023

Link(s)

Abstract

Wearable sweat sensors are gaining significant attention due to their unparalleled potential for noninvasive health monitoring. Sweat, as a kind of body fluid, contains informative physiological indicators that are related to personalized health status. Advances in wearable sweat sampling and routing technologies, flexible, and stretchable materials, and wireless digital technologies have led to the development of integrated sweat sensors that are comfortable, flexible, light, and intelligent. Herein, we report a flexible and integrated wearable device via incorporating a microfluidic system and a sensing chip with skin-integrated electronic format toward in-situ monitoring of uric acid (UA) in sweat that associates with gout, cardiovascular, and renal diseases. The microfluidic system validly realizes the real-time capture perspiration from human skin. The obtained detection range is 5–200 μM and the detection limit is 1.79 μM, which offers an importance diagnostic method for clinical relevant lab test. The soft and flexible features of the constructed device allows it to be mounted onto nearly anywhere on the body. We tested the sweat UA in diverse subjects and various body locations during exercise, and similar trends were also observed by using a commercial UA assay kit. © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Research Area(s)

  • in-situ detection, microchannels, skin-integrated electronics, Sweat sensors, wearable device

Citation Format(s)

Thin, soft, skin-integrated electronics for real-time and wireless detection of uric acid in sweat. / Hu, Yue; Wang, Lan; Li, Jian et al.
In: International Journal of Smart and Nano Materials, Vol. 14, No. 4, 2023, p. 406–419.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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