The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

14 Scopus Citations
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Author(s)

  • M. Salomé Rodríguez-Morgade
  • Ravindra K. Pandey
  • Dennis K. P. Ng
  • Tomás Torres
  • Fabienne Dumoulin

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)1041-1056
Journal / PublicationChemical Society Reviews
Volume49
Issue number4
Online published17 Dec 2019
Publication statusPublished - 21 Feb 2020

Abstract

Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.

Citation Format(s)

The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer. / Lo, Pui-Chi; Rodríguez-Morgade, M. Salomé; Pandey, Ravindra K.; Ng, Dennis K. P.; Torres, Tomás; Dumoulin, Fabienne.

In: Chemical Society Reviews, Vol. 49, No. 4, 21.02.2020, p. 1041-1056.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal