The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
Original language | English |
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Pages (from-to) | 1041-1056 |
Journal / Publication | Chemical Society Reviews |
Volume | 49 |
Issue number | 4 |
Online published | 17 Dec 2019 |
Publication status | Published - 21 Feb 2020 |
Link(s)
Abstract
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of photosensitisers for photodynamic therapy of cancer. Several derivatives are at various phases of clinical trials, and efforts have been put continuously to improve their photodynamic efficacy. To this end, various strategies have been applied to develop advanced phthalocyanines with optimised photoproperties, dual therapeutic actions, tumour-targeting properties and/or specific activation at tumour sites. The advantageous properties and potential of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer are highlighted in this tutorial review.
Research Area(s)
- Phthalocyanine, Photodynamic therapy
Bibliographic Note
Information for this record is supplemented by the author(s) concerned.
Citation Format(s)
The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer. / Lo, Pui-Chi; Rodríguez-Morgade, M. Salomé; Pandey, Ravindra K. et al.
In: Chemical Society Reviews, Vol. 49, No. 4, 21.02.2020, p. 1041-1056.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review