Abstract
In recent years, applications and experimental studies of DNA in nanochannels have stimulated the investigation of the polymer physics of DNA in confinement. Recent advances in the physics of confined polymers, using DNA as a model polymer, have moved beyond the classic Odijk theory for the strong confinement, and the classic blob theory for the weak confinement. In this review, we present the current understanding of the behaviors of confined polymers while briefly reviewing classic theories. Three aspects of confined DNA are presented: static, dynamic, and topological properties. The relevant simulation methods are also summarized. In addition, comparisons of confined DNA with DNA under tension and DNA in semidilute solution are made to emphasize universal behaviors. Finally, an outlook of the possible future research for confined DNA is given.
| Original language | English |
|---|---|
| Pages (from-to) | 80-100 |
| Journal | Advances in Colloid and Interface Science |
| Volume | 232 |
| Online published | 23 Dec 2015 |
| DOIs | |
| Publication status | Published - Jun 2016 |
| Externally published | Yes |
Research Keywords
- Confinement
- DNA
- Monte Carlo simulation
- Nanochannel
- Polymer physics
Fingerprint
Dive into the research topics of 'The polymer physics of single DNA confined in nanochannels'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver