The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

6 Scopus Citations
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Author(s)

  • Chi-Fai Chan
  • Chen Xie
  • Ming-Kiu Tsang
  • Sam Lear
  • Lixiong Dai
  • And 9 others
  • Yan Zhou
  • Jakub Cicho
  • Miroslaw Karbowiak
  • Dariusz Hreniak
  • Rongfeng Lan
  • Steve L. Cobb
  • Michael Hon-Wah Lam
  • Jianhua Hao
  • Ka-Leung Wong

Detail(s)

Original languageEnglish
Pages (from-to)4539-4545
Journal / PublicationEuropean Journal of Inorganic Chemistry
Volume2015
Issue number27
Publication statusPublished - 1 Sep 2015

Abstract

In this work, the shape effect of our same-sized hybrid nanomaterials conjugated with two different Plk1-specific peptides had been investigated in terms of their photophysical properties, cellular uptake efficiencies, and selective inhibitory effects towards cancer and normal cells. The results clearly indicate that our spherical NaGdF4

Research Area(s)

  • Antitumor agents, Imaging agents, Inhibitors, Lanthanides, Medicinal chemistry, Nanoparticles, Peptides

Citation Format(s)

The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors. / Chan, Chi-Fai; Xie, Chen; Tsang, Ming-Kiu; Lear, Sam; Dai, Lixiong; Zhou, Yan; Cicho, Jakub; Karbowiak, Miroslaw; Hreniak, Dariusz; Lan, Rongfeng; Cobb, Steve L.; Lam, Michael Hon-Wah; Hao, Jianhua; Wong, Ka-Leung.

In: European Journal of Inorganic Chemistry, Vol. 2015, No. 27, 01.09.2015, p. 4539-4545.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review