The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors

Chi-Fai Chan; Chen Xie; Ming-Kiu Tsang; Sam Lear; Lixiong Dai; Yan Zhou; Jakub Cicho; Miroslaw Karbowiak; Dariusz Hreniak; Rongfeng Lan; Steve L. Cobb; Michael Hon-Wah Lam; Jianhua Hao; Ka-Leung Wong

doi:10.1002/ejic.201500321

Author(s)

Chi-Fai Chan
Chen Xie
Ming-Kiu Tsang
Sam Lear
Lixiong Dai
And 9 others

Yan Zhou
Jakub Cicho
Miroslaw Karbowiak
Dariusz Hreniak
Rongfeng Lan
Steve L. Cobb
Michael Hon-Wah Lam
Jianhua Hao
Ka-Leung Wong

Detail(s)

Original language	English
Pages (from-to)	4539-4545
Journal / Publication	European Journal of Inorganic Chemistry
Volume	2015
Issue number	27
Publication status	Published - 1 Sept 2015

Link(s)

DOI	DOI https://doi.org/10.1002/ejic.201500321 Final Published version
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Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84942503790&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(8d5e30ba-ee45-4988-9d37-63485763fc5e).html

Abstract

In this work, the shape effect of our same-sized hybrid nanomaterials conjugated with two different Plk1-specific peptides had been investigated in terms of their photophysical properties, cellular uptake efficiencies, and selective inhibitory effects towards cancer and normal cells. The results clearly indicate that our spherical NaGdF₄

Research Area(s)

Antitumor agents, Imaging agents, Inhibitors, Lanthanides, Medicinal chemistry, Nanoparticles, Peptides

SDG 3 - Good Health and Well-being

Citation Format(s)

[ RIS ] [ BibTeX ]

The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors. / Chan, Chi-Fai; Xie, Chen; Tsang, Ming-Kiu et al.
In: European Journal of Inorganic Chemistry, Vol. 2015, No. 27, 01.09.2015, p. 4539-4545.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Chan, C-F, Xie, C, Tsang, M-K, Lear, S, Dai, L, Zhou, Y, Cicho, J, Karbowiak, M, Hreniak, D, Lan, R, Cobb, SL, Lam, MH-W, Hao, J & Wong, K-L 2015, 'The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors', European Journal of Inorganic Chemistry, vol. 2015, no. 27, pp. 4539-4545. https://doi.org/10.1002/ejic.201500321

Chan, C.-F., Xie, C., Tsang, M.-K., Lear, S., Dai, L., Zhou, Y., Cicho, J., Karbowiak, M., Hreniak, D., Lan, R., Cobb, S. L., Lam, M. H.-W., Hao, J., & Wong, K.-L. (2015). The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors. European Journal of Inorganic Chemistry, 2015(27), 4539-4545. https://doi.org/10.1002/ejic.201500321

Chan CF, Xie C, Tsang MK, Lear S, Dai L, Zhou Y et al. The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors. European Journal of Inorganic Chemistry. 2015 Sept 1;2015(27):4539-4545. doi: 10.1002/ejic.201500321

Chan, Chi-Fai ; Xie, Chen ; Tsang, Ming-Kiu et al. / The Effects of Morphology and Linker Length on the Properties of Peptide-Lanthanide Upconversion Nanomaterials as G2 Phase Cell Cycle Inhibitors. In: European Journal of Inorganic Chemistry. 2015 ; Vol. 2015, No. 27. pp. 4539-4545.