The effect of ionic strength on the sensing performance of liquid-gated biosensors

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review

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Detail(s)

Original languageEnglish
Title of host publication2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages242-245
ISBN (Electronic)9781509030286
ISBN (Print)9781509030293
Publication statusPublished - Jul 2017

Publication series

NameProceedings of the IEEE Conference on Nanotechnology
Volume2017
ISSN (Electronic)1944-9380

Conference

Title17th IEEE International Conference on Nanotechnology (IEEE NANO 2017)
LocationPittsburgh Marriott City Center
PlaceUnited States
CityPittsburgh
Period25 - 28 July 2017

Abstract

We experimentally demonstrated that the effect of ionic strength of electrolyte on the electrical signal of liquid-gated graphene field-effect transistors (G-FETs) in sensing of E. coli. Phosphate buffered saline (PBS) with different concentrations, which affects the ionic strength, was employed as the electrolyte for biosensor operation. The results showed that larger response (4.16%) was obtained by using the PBS with smaller ionic strength (1.627 mM). When the ionic strength is too low (0.1627 mM), it causes negative effect on the antibody-E. coli interaction, resulting in a smaller response (2.98%). This study provides a simple method to optimize the operation conditions of graphene biosensors, which enables the optimization of the electrical response.

Citation Format(s)

The effect of ionic strength on the sensing performance of liquid-gated biosensors. / Wu, Guangfu; Tang, Xin; Lin, Zihong; Meyyappan, Meyya; Lai, King Wai Chiu.

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO). Institute of Electrical and Electronics Engineers Inc., 2017. p. 242-245 8117313 (Proceedings of the IEEE Conference on Nanotechnology; Vol. 2017).

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review