Abstract
During the past two decades, a variety of histopathological alterations in fish and bivalves have been developed and used as biomarkers in pollution monitoring. Some of these have been successfully adopted in major national monitoring programmes, while others, although show promise, are still in the experimental stage. This paper critically reviews the scientific basis, cause and effect relationship, reliability, advantages and limitations of 14 histo-cytopathological biomarkers. The usefulness and practical application of each biomarker have been evaluated against a number of objective criteria including: ecological relevance, sensitivity, specificity, dose-response relationship, confounding factors, technical difficulties and cost-effectiveness. © 2004 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 817-834 |
| Journal | Marine Pollution Bulletin |
| Volume | 48 |
| Issue number | 9-10 |
| Online published | 9 Apr 2004 |
| DOIs | |
| Publication status | Published - May 2004 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being -
SDG 14 Life Below Water
Research Keywords
- Biomarkers
- Fish diseases
- Histo-cytopathology
- Marine pollution
- Xenobiotics
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