Ternary Chalcogenide Nanosheets with Ultrahigh Photothermal Conversion Efficiency for Photoacoustic Theranostics

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Houjuan Zhu
  • Zhuangchai Lai
  • Yuan Fang
  • Xu Zhen
  • Xiaoying Qi
  • Dan Ding
  • Peng Chen
  • Kanyi Pu

Detail(s)

Original languageEnglish
Article number1604139
Journal / PublicationSmall
Volume13
Issue number16
Online published10 Feb 2017
Publication statusPublished - 25 Apr 2017
Externally publishedYes

Abstract

2D materials (TDMs) have been explored for photonic theranostics. To achieve deep-tissue penetration, near-infrared (NIR) light is essential for photoacoustic (PA) theranostics. However, because the absorption profiles of existing TDMs are generally featureless with no obvious NIR absorption peaks, their PA signals and therapeutic efficacies are limited. This paper herein reports the synthesis and application of ternary chalcogenide nanosheets (Ta2NiS5-P) for PA theranostics. In contrast to the current TDMs for such application, Ta2NiS5-P has a ternary instead of binary composition. This difference brings in the strong and featured NIR for Ta2NiS5-P. To the best of the knowledge, this is the first example using ternary chalcogenide nanosheets for such application; moreover, the photothermal conversion efficiency of Ta2 NiS5-P is the highest (35%) among all the reported TDMs based on the same calculation method. These advantages allow Ta2NiS5-P to passively target, effectively delineate, and completely eradicate the tumor of living mice after systemic administration.

Research Area(s)

  • 2D materials, photoacoustic imaging, photothermal therapy, theranostics

Citation Format(s)

Ternary Chalcogenide Nanosheets with Ultrahigh Photothermal Conversion Efficiency for Photoacoustic Theranostics. / Zhu, Houjuan; Lai, Zhuangchai; Fang, Yuan; Zhen, Xu; Tan, Chaoliang; Qi, Xiaoying; Ding, Dan; Chen, Peng; Zhang, Hua; Pu, Kanyi.

In: Small, Vol. 13, No. 16, 1604139, 25.04.2017.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal