TY - JOUR
T1 - Tendon tissue engineering using scaffold enhancing strategies
AU - Liu, Yang
AU - Ramanath, H. S.
AU - Wang, Dong-An
N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].
PY - 2008/4
Y1 - 2008/4
N2 - Tendon traumas or diseases are prevalent and debilitating lesions that affect the quality of life among populations worldwide. As a novel solution, tendon tissue engineering aims to address these lesions by integrating engineered, living substitutes with their native counterparts in vivo, thereby restoring the defective functions in situ. For such a purpose, competent scaffolding materials are essential. To date, three major categories of scaffolding materials have been employed: polyesters, polysaccharides, and collagen derivatives. Furthermore, with these materials as a base, a variety of specialized methodologies have been developed or adopted to enhance neo-tendogenesis. These strategies include cellular hybridization, interfacing improvement, and physical stimulation. © 2008 Elsevier Ltd. All rights reserved.
AB - Tendon traumas or diseases are prevalent and debilitating lesions that affect the quality of life among populations worldwide. As a novel solution, tendon tissue engineering aims to address these lesions by integrating engineered, living substitutes with their native counterparts in vivo, thereby restoring the defective functions in situ. For such a purpose, competent scaffolding materials are essential. To date, three major categories of scaffolding materials have been employed: polyesters, polysaccharides, and collagen derivatives. Furthermore, with these materials as a base, a variety of specialized methodologies have been developed or adopted to enhance neo-tendogenesis. These strategies include cellular hybridization, interfacing improvement, and physical stimulation. © 2008 Elsevier Ltd. All rights reserved.
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U2 - 10.1016/j.tibtech.2008.01.003
DO - 10.1016/j.tibtech.2008.01.003
M3 - RGC 21 - Publication in refereed journal
C2 - 18295915
SN - 0167-7799
VL - 26
SP - 201
EP - 209
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 4
ER -