Systematic evaluation of biomarker stability in pilot scale sewer pipes

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Jianfa Gao
  • Jiaying Li
  • Guangming Jiang
  • Adam H. Shypanski
  • Ludwika M. Nieradzik
  • Jochen F. Mueller
  • Christoph Ort
  • Phong K. Thai

Detail(s)

Original languageEnglish
Pages (from-to)447-455
Journal / PublicationWater Research
Volume151
Publication statusPublished - 15 Mar 2019
Externally publishedYes

Abstract

Transformation of biomarkers (or their stability) during sewer transport is an important issue for wastewater-based epidemiology (WBE). Most studies so far have been conducted in the laboratory, which usually employed unrealistic conditions. In the present study, we utilized a pilot sewer system including a gravity pipe and a rising main pipe to investigate the fate of 24 pharmaceutical biomarkers. A programmable logic controller was used to control and monitor the system including sewer operational conditions and wastewater properties. Sequential samples were collected that can represent hydraulic retention time (HRT) of up to 8 h in a rising main and 4 h in a gravity sewer. Wastewater parameters and biomarker concentrations were analysed to evaluate the stability and transformation kinetics. The wastewater parameters of the pilot system were close to the conditions of real sewers. The findings of biomarker transformation were also close to real sewer data with seventeen biomarkers reported as stable while buprenorphine, caffeine, ethyl-sulfate, methadone, paracetamol, paraxanthine and salicylic acid degraded to variable extents. Both zero-order and first-order kinetics were used to model the degradation of unstable biomarkers and interestingly the goodness of fit R2 for the zero-order model was higher than the first-order model for all unstable biomarkers in the rising main. The pilot sewer system simulates more realistic conditions than benchtop laboratory setups and may provide a more accurate approach for assessing the in-sewer transformation kinetics and stability of biomarkers. © 2018 Elsevier Ltd

Research Area(s)

  • Biomarker stability, Gravity sewer, PPCPs, Rising main, Transformation kinetics, Wastewater-based epidemiology

Bibliographic Note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to lbscholars@cityu.edu.hk.

Citation Format(s)

Systematic evaluation of biomarker stability in pilot scale sewer pipes. / Gao, Jianfa; Li, Jiaying; Jiang, Guangming et al.
In: Water Research, Vol. 151, 15.03.2019, p. 447-455.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review