Syringe-pump-induced fluctuation in all-aqueous microfluidic system implications for flow rate accuracy

Zida Li; Sze Yi Mak; Alban Sauret; Ho Cheung Shum

doi:10.1039/c3lc51176f

Syringe-pump-induced fluctuation in all-aqueous microfluidic system implications for flow rate accuracy

Zida Li
, Sze Yi Mak
, Alban Sauret
, Ho Cheung Shum

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

157 Citations (Scopus)

Abstract

We report a new method to display the minute fluctuations induced by syringe pumps on microfluidic flows by using a liquid-liquid system with an ultralow interfacial tension. We demonstrate that the stepper motor inside the pump is a source of fluctuations in microfluidic flows by comparing the frequencies of the ripples observed at the interface to that of the pulsation of the stepper motor. We also quantify the fluctuations induced at different flow rates, using syringes of different diameters, and using different syringe pumps with different advancing distances per step. Our work provides a way to predict the frequency of the fluctuation that the driving syringe pump induces on a microfluidic system and suggests that syringe pumps can be a source of fluctuations in microfluidic flows, thus contributing to the polydispersity of the resulting droplets. © 2014 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	744-749
Journal	Lab on a Chip
Volume	14
Issue number	4
DOIs	https://doi.org/10.1039/c3lc51176f
Publication status	Published - 21 Feb 2014
Externally published	Yes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Funding

This research was supported by the Early Career Scheme (HKU 707712P) from the Research Grants Council of Hong Kong, the Basic Research Program-General Program (JC201105190878A) from the Science and Technology Innovation Commission of Shenzhen Municipality, the Young Scholars Program (NSFC51206138/E0605) from the National Natural Science Foundation of China, as well as the Small Project Funding (201109176165) and the University Development Fund (UDF) on A Soft Lithography System for Fabrication of Microfluidic Devices from the University of Hong Kong.

RGC Funding Information

RGC-funded

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abstract = "We report a new method to display the minute fluctuations induced by syringe pumps on microfluidic flows by using a liquid-liquid system with an ultralow interfacial tension. We demonstrate that the stepper motor inside the pump is a source of fluctuations in microfluidic flows by comparing the frequencies of the ripples observed at the interface to that of the pulsation of the stepper motor. We also quantify the fluctuations induced at different flow rates, using syringes of different diameters, and using different syringe pumps with different advancing distances per step. Our work provides a way to predict the frequency of the fluctuation that the driving syringe pump induces on a microfluidic system and suggests that syringe pumps can be a source of fluctuations in microfluidic flows, thus contributing to the polydispersity of the resulting droplets. {\textcopyright} 2014 The Royal Society of Chemistry.",

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AU - Sauret, Alban

AU - Shum, Ho Cheung

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

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AB - We report a new method to display the minute fluctuations induced by syringe pumps on microfluidic flows by using a liquid-liquid system with an ultralow interfacial tension. We demonstrate that the stepper motor inside the pump is a source of fluctuations in microfluidic flows by comparing the frequencies of the ripples observed at the interface to that of the pulsation of the stepper motor. We also quantify the fluctuations induced at different flow rates, using syringes of different diameters, and using different syringe pumps with different advancing distances per step. Our work provides a way to predict the frequency of the fluctuation that the driving syringe pump induces on a microfluidic system and suggests that syringe pumps can be a source of fluctuations in microfluidic flows, thus contributing to the polydispersity of the resulting droplets. © 2014 The Royal Society of Chemistry.

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DO - 10.1039/c3lc51176f

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SN - 1473-0197

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SP - 744

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JO - Lab on a Chip

JF - Lab on a Chip

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Syringe-pump-induced fluctuation in all-aqueous microfluidic system implications for flow rate accuracy

Abstract

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