Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Yulia M. Ohorodnik
  • Sikalov A. Alexander
  • Dmytro M. Khomenko
  • Roman O. Doroshchuk
  • Ilona V. Raspertova
  • Sergiu Shova
  • Rostyslav D. Lampeka

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)213–221
Journal / PublicationTransition Metal Chemistry
Volume47
Issue number6
Online published12 Jul 2022
Publication statusPublished - Aug 2022

Abstract

The structures of new p-cymene Ru(II) complexes with 2-(1-methyl-1H-1,2,4-triazol-3-yl)pyridine and 2-(1-methyl-1H-1,2,4-triazol-5-yl)pyridine were established based on the results of elemental analysis; IR and NMR spectra; and X-ray diffraction studies. Their anticancer activity, tested on human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780cis (cisplatin-resistant), is also reported.

Citation Format(s)

Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines. / Ohorodnik, Yulia M.; Alexander, Sikalov A.; Khomenko, Dmytro M. et al.

In: Transition Metal Chemistry, Vol. 47, No. 6, 08.2022, p. 213–221.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review