Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines

Yulia M. Ohorodnik; Sikalov A. Alexander; Dmytro M. Khomenko; Roman O. Doroshchuk; Ilona V. Raspertova; Sergiu Shova; Maria V. Babak; Rostyslav D. Lampeka

doi:10.1007/s11243-022-00503-w

Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines

Yulia M. Ohorodnik
, Sikalov A. Alexander
, Dmytro M. Khomenko
, Roman O. Doroshchuk
, Ilona V. Raspertova
, Sergiu Shova^*
, Maria V. Babak
, Rostyslav D. Lampeka^*

^*Corresponding author for this work

Department of Chemistry

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

6 Citations (Scopus)

Abstract

The structures of new p-cymene Ru(II) complexes with 2-(1-methyl-1H-1,2,4-triazol-3-yl)pyridine and 2-(1-methyl-1H-1,2,4-triazol-5-yl)pyridine were established based on the results of elemental analysis; IR and NMR spectra; and X-ray diffraction studies. Their anticancer activity, tested on human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780cis (cisplatin-resistant), is also reported.

Original language	English
Pages (from-to)	213–221
Journal	Transition Metal Chemistry
Volume	47
Issue number	6
Online published	12 Jul 2022
DOIs	https://doi.org/10.1007/s11243-022-00503-w
Publication status	Published - Aug 2022

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Ohorodnik, Y. M., Alexander, S. A., Khomenko, D. M., Doroshchuk, R. O., Raspertova, I. V., Shova, S., Babak, M. V., & Lampeka, R. D. (2022). Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines. Transition Metal Chemistry, 47(6), 213–221. https://doi.org/10.1007/s11243-022-00503-w

@article{03ef38ba968841548d3592c565665e47,

title = "Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines",

abstract = "The structures of new p-cymene Ru(II) complexes with 2-(1-methyl-1H-1,2,4-triazol-3-yl)pyridine and 2-(1-methyl-1H-1,2,4-triazol-5-yl)pyridine were established based on the results of elemental analysis; IR and NMR spectra; and X-ray diffraction studies. Their anticancer activity, tested on human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780cis (cisplatin-resistant), is also reported.",

author = "Ohorodnik, \{Yulia M.\} and Alexander, \{Sikalov A.\} and Khomenko, \{Dmytro M.\} and Doroshchuk, \{Roman O.\} and Raspertova, \{Ilona V.\} and Sergiu Shova and Babak, \{Maria V.\} and Lampeka, \{Rostyslav D.\}",

year = "2022",

month = aug,

doi = "10.1007/s11243-022-00503-w",

language = "English",

volume = "47",

pages = "213–221",

journal = "Transition Metal Chemistry",

issn = "0340-4285",

publisher = "Springer Netherlands",

number = "6",

}

Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines. / Ohorodnik, Yulia M.; Alexander, Sikalov A.; Khomenko, Dmytro M. et al.
In: Transition Metal Chemistry, Vol. 47, No. 6, 08.2022, p. 213–221.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Synthesis, structural characterization and anticancer properties of p-cymene Ru(II) complexes with 2-(N-methyl-1H-1,2,4-triazol-3-yl)pyridines

AU - Ohorodnik, Yulia M.

AU - Alexander, Sikalov A.

AU - Khomenko, Dmytro M.

AU - Doroshchuk, Roman O.

AU - Raspertova, Ilona V.

AU - Shova, Sergiu

AU - Babak, Maria V.

AU - Lampeka, Rostyslav D.

PY - 2022/8

Y1 - 2022/8

N2 - The structures of new p-cymene Ru(II) complexes with 2-(1-methyl-1H-1,2,4-triazol-3-yl)pyridine and 2-(1-methyl-1H-1,2,4-triazol-5-yl)pyridine were established based on the results of elemental analysis; IR and NMR spectra; and X-ray diffraction studies. Their anticancer activity, tested on human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780cis (cisplatin-resistant), is also reported.

AB - The structures of new p-cymene Ru(II) complexes with 2-(1-methyl-1H-1,2,4-triazol-3-yl)pyridine and 2-(1-methyl-1H-1,2,4-triazol-5-yl)pyridine were established based on the results of elemental analysis; IR and NMR spectra; and X-ray diffraction studies. Their anticancer activity, tested on human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780cis (cisplatin-resistant), is also reported.

UR - https://www.scopus.com/pages/publications/85134259034

UR - https://www.scopus.com/pages/publications/85134259034#tab=impact

U2 - 10.1007/s11243-022-00503-w

DO - 10.1007/s11243-022-00503-w

M3 - RGC 21 - Publication in refereed journal

SN - 0340-4285

VL - 47

SP - 213

EP - 221

JO - Transition Metal Chemistry

JF - Transition Metal Chemistry

IS - 6

ER -