Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

326 Scopus Citations
View graph of relations

Author(s)

  • Malgorzata Wojtoniszak
  • Xuecheng Chen
  • Ryszard J. Kalenczuk
  • Anna Wajda
  • Joanna Łapczuk
  • Mateusz Kurzewski
  • Marek Drozdzik
  • Ewa Borowiak-Palen

Detail(s)

Original languageEnglish
Pages (from-to)79-85
Journal / PublicationColloids and Surfaces B: Biointerfaces
Volume89
Issue number1
Publication statusPublished - 1 Jan 2012

Abstract

The synthesis, characterization, and toxicity of graphene oxide and reduced graphene oxide are reported. Prior to the cytocompatibility tests the stability of the suspensions in a wide range of concentrations (3.125-100 μg/mL) of three different dispersants is studied. Polyethylene glycol (PEG), polyethylene glycol-polypropylene glycol-polyethylene glycol (Pluronic P123), and sodium deoxycholate (DOC) are investigated as the dispersants. The toxicity depends on the type of dispersant and concentration of the nanomaterials in the suspensions. Detailed analysis suggests that graphene oxide functionalized with PEG in the concentration range between 3125 μg/mL and 25 μg/mL exhibits the best biocompatibility with mice fibroblast cells (line L929). © 2011 Elsevier B.V.

Research Area(s)

  • Graphene, Graphene oxide, In vitro toxicology

Citation Format(s)

Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide. / Wojtoniszak, Malgorzata; Chen, Xuecheng; Kalenczuk, Ryszard J.; Wajda, Anna; Łapczuk, Joanna; Kurzewski, Mateusz; Drozdzik, Marek; Chu, Pual K.; Borowiak-Palen, Ewa.

In: Colloids and Surfaces B: Biointerfaces, Vol. 89, No. 1, 01.01.2012, p. 79-85.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review