Synthesis and in vitro photodynamic activity of novel galactose-containing phthalocyanines

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Priscilla P. S. Lee
  • Elaine Y. M. Chan
  • Wing-Ping Fong
  • Wing-Hung Ko
  • Dennis K. P. Ng

Detail(s)

Original languageEnglish
Pages (from-to)1551-1554
Journal / PublicationTetrahedron Letters
Volume46
Issue number9
Publication statusPublished - 28 Feb 2005
Externally publishedYes

Abstract

A novel series of silicon(IV) phthalocyanines with one or two axial acetal-protected galactose substituent(s) have been prepared by typical substitution reactions. The compounds exhibit a high photodynamic activity against HepG2 human hepatocarcinoma cells with IC50 values down to 0.10 μM. © 2005 Elsevier Ltd. All rights reserved.

Citation Format(s)

Synthesis and in vitro photodynamic activity of novel galactose-containing phthalocyanines. / Lee, Priscilla P. S.; Lo, Pui-Chi; Chan, Elaine Y. M.; Fong, Wing-Ping; Ko, Wing-Hung; Ng, Dennis K. P.

In: Tetrahedron Letters, Vol. 46, No. 9, 28.02.2005, p. 1551-1554.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review