Synthesis and antitumor activity of a series of osmium(vi) nitrido complexes bearing quinolinolato ligands

Quan Tang; Wen-Xiu Ni; Chi-Fai Leung; Wai-Lun Man; Kenneth King-Kwan Lau; Yimin Liang; Yun-Wah Lam; Wai-Yeung Wong; Shie-Ming Peng; Gui-Jian Liu; Tai-Chu Lau

doi:10.1039/c3cc42250j

Synthesis and antitumor activity of a series of osmium(vi) nitrido complexes bearing quinolinolato ligands

Quan Tang, Wen-Xiu Ni, Chi-Fai Leung, Wai-Lun Man, Kenneth King-Kwan Lau, Yimin Liang, Yun-Wah Lam, Wai-Yeung Wong, Shie-Ming Peng, Gui-Jian Liu, Tai-Chu Lau

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

35 Citations (Scopus)

Abstract

A series of osmium(vi) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that Os^VIN is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

Original language	English
Pages (from-to)	9980-9982
Journal	Chemical Communications
Volume	49
Issue number	85
Online published	28 Aug 2013
DOIs	https://doi.org/10.1039/c3cc42250j
Publication status	Published - 4 Nov 2013

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title = "Synthesis and antitumor activity of a series of osmium(vi) nitrido complexes bearing quinolinolato ligands",

abstract = "A series of osmium(vi) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVIN is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs. ",

author = "Quan Tang and Wen-Xiu Ni and Chi-Fai Leung and Wai-Lun Man and Lau, {Kenneth King-Kwan} and Yimin Liang and Yun-Wah Lam and Wai-Yeung Wong and Shie-Ming Peng and Gui-Jian Liu and Tai-Chu Lau",

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TY - JOUR

T1 - Synthesis and antitumor activity of a series of osmium(vi) nitrido complexes bearing quinolinolato ligands

AU - Tang, Quan

AU - Ni, Wen-Xiu

AU - Leung, Chi-Fai

AU - Man, Wai-Lun

AU - Lau, Kenneth King-Kwan

AU - Liang, Yimin

AU - Lam, Yun-Wah

AU - Wong, Wai-Yeung

AU - Peng, Shie-Ming

AU - Liu, Gui-Jian

AU - Lau, Tai-Chu

PY - 2013/11/4

Y1 - 2013/11/4

N2 - A series of osmium(vi) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVIN is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

AB - A series of osmium(vi) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVIN is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84885155074&origin=recordpage

U2 - 10.1039/c3cc42250j

DO - 10.1039/c3cc42250j

M3 - RGC 21 - Publication in refereed journal

C2 - 24042270

SN - 0009-241X

VL - 49

SP - 9980

EP - 9982

JO - Chemical Communications

JF - Chemical Communications

IS - 85

ER -

Synthesis and antitumor activity of a series of osmium(vi) nitrido complexes bearing quinolinolato ligands

Abstract

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