Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium

Guodong Jin; Hui Qin; Huiliang Cao; Shi Qian; Yaochao Zhao; Xiaochun Peng; Xianlong Zhang; Xuanyong Liu; Paul K. Chu

doi:10.1016/j.biomaterials.2014.05.074

Author(s)

Guodong Jin
Hui Qin
Huiliang Cao
Shi Qian
Yaochao Zhao
Xiaochun Peng
Xianlong Zhang
Xuanyong Liu

Detail(s)

Original language	English
Pages (from-to)	7699-7713
Journal / Publication	Biomaterials
Volume	35
Issue number	27
Online published	16 Jun 2014
Publication status	Published - Sep 2014

Link(s)

DOI	DOI https://doi.org/10.1016/j.biomaterials.2014.05.074 Final Published version
	Check@CityULib
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84903471743&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(a152c746-96d9-43c3-90f0-404b23d60c89).html

Abstract

Zinc (Zn) and silver (Ag) are co-implanted into titanium by plasma immersion ion implantation. A Zn containing film with Ag nanoparticles (Ag NPs) possessing a wide size distribution is formed on the surface and the corrosion resistance is improved due to the micro-galvanic couples formed by the implanted Zn and Ag. Not only are the initial adhesion, spreading, proliferation and osteogenic differentiation of rBMSCs observed from the Zn/Ag implanted Ti invitro, but also bacteria killing is achieved both invitro and invivo. Electrochemical polarization and ion release measurements suggest that the excellent osteogenic activity and antibacterial ability of the Zn/Ag co-implanted titanium are related to the synergistic effect resulting from the long-range interactions of the released Zn ions and short-range interactions of the embedded Ag NPs. The Zn/Ag co-implanted titanium offers both excellent osteogenic activity and antibacterial ability and has large potential in orthopedic and dental implants. © 2014 Elsevier Ltd.

Research Area(s)

Antibacterial ability, Ion implantation, Osteogenic activity, Silver, Titanium, Zinc

Citation Format(s)

[ RIS ] [ BibTeX ]

Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium. / Jin, Guodong; Qin, Hui; Cao, Huiliang et al.

In: Biomaterials, Vol. 35, No. 27, 09.2014, p. 7699-7713.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Jin, G, Qin, H, Cao, H, Qian, S, Zhao, Y, Peng, X, Zhang, X, Liu, X & Chu, PK 2014, 'Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium', Biomaterials, vol. 35, no. 27, pp. 7699-7713. https://doi.org/10.1016/j.biomaterials.2014.05.074

Jin, G., Qin, H., Cao, H., Qian, S., Zhao, Y., Peng, X., Zhang, X., Liu, X., & Chu, P. K. (2014). Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium. Biomaterials, 35(27), 7699-7713. https://doi.org/10.1016/j.biomaterials.2014.05.074

Jin G, Qin H, Cao H, Qian S, Zhao Y, Peng X et al. Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium. Biomaterials. 2014 Sep;35(27):7699-7713. Epub 2014 Jun 16. doi: 10.1016/j.biomaterials.2014.05.074

Jin, Guodong ; Qin, Hui ; Cao, Huiliang et al. / Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium. In: Biomaterials. 2014 ; Vol. 35, No. 27. pp. 7699-7713.