Surface Modification of Biomaterials by Plasma-based Technology

The interactions between biomaterials and biological tissues and fluids depends on the surface properties of the biomaterials and associated biological responses. However, biomaterials having the favorable bulk may not produce the pre-designed biological functions and surface modification is frequently performed. By using plasma-based technology, selected surface properties can be modified while the desirable bulk properties can be preserved. Plasma immersion ion implantation and deposition (PIII&D) is one of the widely used plasma-based surface treatment techniques for biomaterials and biomedical implants. The interface between biodegradable biomaterials and tissues and body fluids is dynamic and PIII&D offers the unique capability of tailoring the interfacial chemistry to ensure controlled degradation. In this distinguished invited presentation, recent research conducted in the Plasma Laboratory of City University of Hong Kong related to plasma treatment of biomaterials and biomedical devices, especially biodegradable ones, will be described.