Stable and ultrasensitive analysis of organic pollutants and heavy metals by dried droplet method with superhydrophobic-induced enrichment

Herein, a dried droplet method (DDM) with superhydrophobic-induced enrichment is reported for stable and ultrasensitive analysis of organic pollutants and heavy metals. A superhydrophobic (SHB) substrate was prepared as an analytical detection platform for the DDM. This SHB substrate was synthesized by sequentially coating polydimethylsiloxane (PDMS) and titanium dioxide nanoparticles (TiO₂ NPs) onto glass substrate surface. In the droplet drying process, the SHB substrate was demonstrated to suppress the coffee ring effect (CRE) and enriched analyte concentration. Combining with Raman spectroscopy for analysis of methylene blue (MB), and with laser-induced breakdown spectroscopy (LIBS) for analysis of chromium (Cr), the results indicated high stability and ultra-sensitivity for organic pollutants and heavy metals detection. Overall, the DDM with superhydrophobic-induced enrichment has big potential in applications requiring stable and ultrasensitive analysis.