Spirochaetes as intestinal pathogens : Lessons from a Brachyspira genome

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)62_Review of books or of software (or similar publications/items)peer-review

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Original languageEnglish
Article number10
Journal / PublicationGut Pathogens
Volume1
Issue number10
Online published1 May 2009
Publication statusPublished - 2009
Externally publishedYes

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Abstract

Anaerobic spirochaetes of the genus Brachyspira have long been known as important gut pathogens of pigs, but increasingly they are recognised as causing disease in birds and other animal species, including human beings. The genome sequence of the major swine pathogen Brachyspira hyodysenteriae was recently published, and this revealed extensive genome optimisation that leads to adaptation to the complex environment of the colon. The genome sequences of other pathogenic and non-pathogenic Brachyspira species are becoming available, and this data will help to reveal how these species have evolved and adapted to varied lifestyles in the large intestines of different species, and why some but not others can induce colitis and diarrhoea

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Spirochaetes as intestinal pathogens: Lessons from a Brachyspira genome. / Hampson, David J; Ahmed, Niyaz.
In: Gut Pathogens, Vol. 1, No. 10, 10, 2009.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)62_Review of books or of software (or similar publications/items)peer-review

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