Sphingolipid profiles differ between adipose tissue depots in Holstein bulls

Á. Kenéz*, S. Bäβler, C. Koch, T. Scheu, K. Huber

*Corresponding author for this work

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

Abstract

Sphingolipids are well-known modulators of metabolic pathways which may contribute to the metabolic differences between adipose tissues. This study aimed to characterise depot-specific sphingolipid profiles in bovine adipose tissues. Subcutaneous (SCAT) and retroperitoneal adipose tissue (RPAT) samples of 6 Holstein bulls were analysed by a targeted metabolomics approach. Abundance of several sphingolipids were different between the depots. Particularly ceramides associated with insulin resistance were higher abundant in RPAT. Assuming that these signals can be released into the circulation, a higher metabolic activity of RPAT might favour insulin resistance.
Original languageEnglish
Title of host publicationEnergy and protein metabolism and nutrition
Subtitle of host publication6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition
EditorsMario Luiz Chizzotti
Place of PublicationThe Netherlands
PublisherWageningen Academic Publishers
Pages233-234
ISBN (Electronic)978-90-8686-891-9
ISBN (Print)978-90-8686-340-2
DOIs
Publication statusPublished - Sept 2019
Event6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition - Belo Horizonte, Belize
Duration: 9 Sept 201912 Sept 2019

Publication series

NameEAAP Scientific Series
PublisherWageningen Academic Publishers
Number138
ISSN (Print)0071-2477

Conference

Conference6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition
Country/TerritoryBelize
CityBelo Horizonte
Period9/09/1912/09/19

Research Keywords

  • cattle
  • ceramides
  • metabolomics
  • visceral adipose tissue

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