Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

3 Scopus Citations
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Detail(s)

Original languageEnglish
Pages (from-to)431-435
Journal / PublicationRSC Chemical Biology
Volume3
Issue number4
Online published10 Mar 2022
Publication statusPublished - 1 Apr 2022

Link(s)

Abstract

We study and uncover the effect of hairpin structures in loops of G-quadruplexes using spectroscopic methods. Notably, we show that the sequence, structure, and position of the hairpin loop control the spectroscopic properties of long loop G-quadruplexes, and highlight that intrinsic fluorescence can be used to monitor the formation of non-canonical G-quadruplexes.

Research Area(s)

  • INTRINSIC FLUORESCENCE, SEQUENCE

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