Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
| Original language | English |
|---|---|
| Pages (from-to) | 2616-2619 |
| Journal / Publication | Chemical Communications |
| Volume | 55 |
| Issue number | 18 |
| Online published | 29 Jan 2019 |
| Publication status | Published - 4 Mar 2019 |
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Abstract
Here we investigate and reveal the effect of bulge position and bulge identity on G-quadruplexes using label-free spectroscopic techniques. Notably, we report significant differences in the spectroscopic features of bulged DNA and RNA G-quadruplexes, and demonstrate that intrinsic fluorescence can be generally used to detect the formation of canonical and non-canonical G-quadruplexes.
Citation Format(s)
Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures. / Chan, Chun-Yin; Umar, Mubarak I.; Kwok, Chun Kit.
In: Chemical Communications, Vol. 55, No. 18, 04.03.2019, p. 2616-2619.
In: Chemical Communications, Vol. 55, No. 18, 04.03.2019, p. 2616-2619.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
