Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

20 Scopus Citations
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Author(s)

  • Yusong Wang
  • Daniel Aili
  • Robert Selegård
  • Yeeyan Tay
  • Lars Baltzer
  • Bo Liedberg

Detail(s)

Original languageEnglish
Pages (from-to)20368-20373
Journal / PublicationJournal of Materials Chemistry
Volume22
Issue number38
Online published8 Aug 2012
Publication statusPublished - 11 Sep 2012
Externally publishedYes

Abstract

Anisotropic nanoparticles stabilized by cetyltrimethylammonium bromide (CTAB) are notoriously difficult to homogenously functionalize using conventional gold-thiol chemistry. Using surface assisted laser desorption time of flight mass spectroscopy and scanning transmission electron microscopy-energy dispersive X-ray spectroscopy, we demonstrate that silver species adsorbed on the particle surface prevent effective surface functionalization. When covered by a thin gold film, particle functionalization was drastically improved. A thiol-containing polypeptide was immobilized on arrowhead gold nanorods (NRs) and was subsequently able to selectively heteroassociate with a complementary polypeptide resulting in a folding-mediated bridging aggregation of the NRs. Despite using arrowhead NRs with a pronounced difference in surface arrangement on the {111} facets on the arrowheads compared to the {100} facets at the particle sides, the polypeptides were efficiently and homogeneously immobilized on the particles after gold film overgrowth.

Citation Format(s)

Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly. / Wang, Yusong; Aili, Daniel; Selegård, Robert; Tay, Yeeyan; Baltzer, Lars; Zhang, Hua; Liedberg, Bo.

In: Journal of Materials Chemistry, Vol. 22, No. 38, 11.09.2012, p. 20368-20373.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review