Source contributions and mass loadings for chemicals of emerging concern : Chemometric application of pharmaco-signature in different aquatic systems

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Jheng-Jie Jiang
  • Chon-Lin Lee
  • Peter Brimblecombe
  • Lucie Vydrova
  • Meng-Der Fang

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)79-86
Journal / PublicationEnvironmental Pollution
Volume208
Publication statusPublished - 1 Jan 2016

Abstract

To characterize the source contributions of chemicals of emerging concern (CECs) from different aquatic environments of Taiwan, we collected water samples from different aquatic systems, which were screened for 30 pharmaceuticals and illicit drugs. The total estimated mass loadings of CECs were 23.1 g/d in southern aquatic systems and 133 g/d in central aquatic systems. We developed an analytical framework combining pollutant fingerprinting, hierarchical cluster analysis (HCA), and principal component analysis with multiple linear regression (PCA-MLR) to infer the pharmaco-signature and source contributions of CECs. Based on this approach, we estimate source contributions of 62.2% for domestic inputs, 16.9% for antibiotics application, and 20.9% for drug abuse/medication in southern aquatic system, compared with 47.3% domestic, 35.1% antibiotic, and 17.6% drug abuse/medication inputs to central aquatic systems. The proposed pharmaco-signature method provides initial insights into the profile and source apportionment of CECs in complex aquatic systems, which are of importance for environmental management.

Research Area(s)

  • Emerging contaminants, Fingerprinting, Mass loading, Risk quotient, Source apportionment

Citation Format(s)

Source contributions and mass loadings for chemicals of emerging concern: Chemometric application of pharmaco-signature in different aquatic systems. / Jiang, Jheng-Jie; Lee, Chon-Lin; Brimblecombe, Peter et al.
In: Environmental Pollution, Vol. 208, 01.01.2016, p. 79-86.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review