TY - GEN
T1 - SNR-enhanced fiber-laser ultrasound sensors for photoacoustic tomography∗
AU - Liang, Yizhi
AU - Jin, Long
AU - Ma, Jun
AU - Wang, Lidai
N1 - Full text of this publication does not contain sufficient affiliation information. With consent from the author(s) concerned, the Research Unit(s) information for this record is based on the existing academic department affiliation of the author(s).
PY - 2020/2
Y1 - 2020/2
N2 - Optical detection of ultrasound for photoacoustic imaging has received great interest. Recently, we have developed a new fiber-optic ultrasound sensor by exploiting dual-polarization fiber laser. It offers high sensitivity (40 Pa over 50 MHz) as well as good stability as a result of the self-heterodyning detection. In this work, the signal-to-noise ratio has been enhanced by suppressing the noise of the ultrasound sensing system via signal averaging. As a result of multiple measurements of a single photoacoustic signal, the total noise was reduced by 40%. With the enhanced detection capability, the sensors have been deployed as photoacoustic probes in different imaging modalities. We demonstrate fastscanning photoacoustic microscopy with a field-of-view 2×2 mm2, a frame rate of 2 Hz to visualize the blood flow dynamics. By bending the flexible fiber optic sensor for geometrical focusing, PACT was realized to image a mouse brain with a spatial resolution of 70 μm. An all-fiber photoacoustic endoscope was built to in vivo image the vascular network of a rat rectum, with a lateral resolution of 10 μm, with a 2.3-mm probe diameter.
AB - Optical detection of ultrasound for photoacoustic imaging has received great interest. Recently, we have developed a new fiber-optic ultrasound sensor by exploiting dual-polarization fiber laser. It offers high sensitivity (40 Pa over 50 MHz) as well as good stability as a result of the self-heterodyning detection. In this work, the signal-to-noise ratio has been enhanced by suppressing the noise of the ultrasound sensing system via signal averaging. As a result of multiple measurements of a single photoacoustic signal, the total noise was reduced by 40%. With the enhanced detection capability, the sensors have been deployed as photoacoustic probes in different imaging modalities. We demonstrate fastscanning photoacoustic microscopy with a field-of-view 2×2 mm2, a frame rate of 2 Hz to visualize the blood flow dynamics. By bending the flexible fiber optic sensor for geometrical focusing, PACT was realized to image a mouse brain with a spatial resolution of 70 μm. An all-fiber photoacoustic endoscope was built to in vivo image the vascular network of a rat rectum, with a lateral resolution of 10 μm, with a 2.3-mm probe diameter.
KW - Fiber optic sensors
KW - Photoacoustic tomography
KW - Ultrasound sensor
UR - https://www.scopus.com/pages/publications/85082645854
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85082645854&origin=recordpage
U2 - 10.1117/12.2542925
DO - 10.1117/12.2542925
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 9781510632431
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
A2 - Oraevsky, Alexander A.
A2 - Wang, Lihong V.
PB - SPIE
T2 - Photons Plus Ultrasound 2020
Y2 - 2 February 2020 through 5 February 2020
ER -