Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole

Ping Wang; Chong-Jing Zhang; Ganchao Chen; Zhenkun Na; Shao Q. Yao; Hongyan Sun

doi:10.1039/c3cc43566k

Author(s)

Chong-Jing Zhang
Ganchao Chen
Zhenkun Na
Shao Q. Yao

Related Research Unit(s)

Shenzhen Research Institute

Detail(s)

Original language	English
Pages (from-to)	8644-8646
Journal / Publication	Chemical Communications
Volume	49
Issue number	77
Online published	31 Jul 2013
Publication status	Published - 7 Oct 2013

Link(s)

DOI	DOI https://doi.org/10.1039/c3cc43566k Final Published version
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Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84883344282&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(d7730025-04b6-4204-b002-049ddf40f202).html

Abstract

We report herein a new site-specific microarray immobilization method based on a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole (CBT). This immobilization strategy has been successfully applied to anchor small molecules, peptides and proteins onto microarrays. © 2013 The Royal Society of Chemistry.

Citation Format(s)

[ RIS ] [ BibTeX ]

Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole. / Wang, Ping; Zhang, Chong-Jing; Chen, Ganchao; Na, Zhenkun; Yao, Shao Q.; Sun, Hongyan.

In: Chemical Communications, Vol. 49, No. 77, 07.10.2013, p. 8644-8646.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Wang, P, Zhang, C-J, Chen, G, Na, Z, Yao, SQ & Sun, H 2013, 'Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole', Chemical Communications, vol. 49, no. 77, pp. 8644-8646. https://doi.org/10.1039/c3cc43566k

Wang, P., Zhang, C-J., Chen, G., Na, Z., Yao, S. Q., & Sun, H. (2013). Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole. Chemical Communications, 49(77), 8644-8646. https://doi.org/10.1039/c3cc43566k

Wang P, Zhang C-J, Chen G, Na Z, Yao SQ, Sun H. Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole. Chemical Communications. 2013 Oct 7;49(77):8644-8646. https://doi.org/10.1039/c3cc43566k

Wang, Ping ; Zhang, Chong-Jing ; Chen, Ganchao ; Na, Zhenkun ; Yao, Shao Q. ; Sun, Hongyan. / Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole. In: Chemical Communications. 2013 ; Vol. 49, No. 77. pp. 8644-8646.