Single living cell refractometry using FBG-based resonant cavity

L. K. Chin; C. S. Lim; P. H. Yap; J. H. Ng; J. Z. Hao; S. Takahashi; A. Q. Liu

doi:10.1109/SENSOR.2007.4300264

Single living cell refractometry using FBG-based resonant cavity

L. K. Chin, C. S. Lim, P. H. Yap, J. H. Ng, J. Z. Hao, S. Takahashi, A. Q. Liu

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

3 Citations (Scopus)

Abstract

This paper reports a single cell refractometer consists of FBG fiber-based resonant cavity by employing buffer modulation method. In this biophotonic chip, single cell is trapped optically in the cavity, and the transmission spectral shifts due to the change of surrounding buffer, without and with cell, are used to determine the cell's refractive index (RI) and size. The measurement shows that MDCK cell has an effective RI of 1.383 at a precision of 0.1%. Moreover, the measurement method with optical trapping eliminates uncertain factors and prevents cell damage. The chip is promising for label-free cell measurement and further cell analysis. ©2007 IEEE.

Original language	English
Title of host publication	TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages	851-854
DOIs	https://doi.org/10.1109/SENSOR.2007.4300264
Publication status	Published - 2007
Externally published	Yes
Event	4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07 - Lyon, France Duration: 10 Jun 2007 → 14 Jun 2007

Publication series

Name	TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

Conference	4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07
Country/Territory	France
City	Lyon
Period	10/06/07 → 14/06/07

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Research Keywords

Buffer modulation and refractive index
Fiber bragg gratings
Single cell measurement

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Chin, L. K., Lim, C. S., Yap, P. H., Ng, J. H., Hao, J. Z., Takahashi, S., & Liu, A. Q. (2007). Single living cell refractometry using FBG-based resonant cavity. In TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 851-854). Article 4300264 (TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems). https://doi.org/10.1109/SENSOR.2007.4300264

@inproceedings{088a60ae9659437e9116ff85d17d4791,

title = "Single living cell refractometry using FBG-based resonant cavity",

abstract = "This paper reports a single cell refractometer consists of FBG fiber-based resonant cavity by employing buffer modulation method. In this biophotonic chip, single cell is trapped optically in the cavity, and the transmission spectral shifts due to the change of surrounding buffer, without and with cell, are used to determine the cell's refractive index (RI) and size. The measurement shows that MDCK cell has an effective RI of 1.383 at a precision of 0.1%. Moreover, the measurement method with optical trapping eliminates uncertain factors and prevents cell damage. The chip is promising for label-free cell measurement and further cell analysis. {\textcopyright}2007 IEEE.",

keywords = "Buffer modulation and refractive index, Fiber bragg gratings, Single cell measurement",

author = "Chin, {L. K.} and Lim, {C. S.} and Yap, {P. H.} and Ng, {J. H.} and Hao, {J. Z.} and S. Takahashi and Liu, {A. Q.}",

note = "Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].; 4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07 ; Conference date: 10-06-2007 Through 14-06-2007",

year = "2007",

doi = "10.1109/SENSOR.2007.4300264",

language = "English",

isbn = "1424408423",

series = "TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems",

pages = "851--854",

booktitle = "TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems",

}

Chin, LK, Lim, CS, Yap, PH, Ng, JH, Hao, JZ, Takahashi, S & Liu, AQ 2007, Single living cell refractometry using FBG-based resonant cavity. in TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems., 4300264, TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems, pp. 851-854, 4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07, Lyon, France, 10/06/07. https://doi.org/10.1109/SENSOR.2007.4300264

Single living cell refractometry using FBG-based resonant cavity. / Chin, L. K.; Lim, C. S.; Yap, P. H. et al.
TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems. 2007. p. 851-854 4300264 (TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Single living cell refractometry using FBG-based resonant cavity

AU - Chin, L. K.

AU - Lim, C. S.

AU - Yap, P. H.

AU - Ng, J. H.

AU - Hao, J. Z.

AU - Takahashi, S.

AU - Liu, A. Q.

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2007

Y1 - 2007

N2 - This paper reports a single cell refractometer consists of FBG fiber-based resonant cavity by employing buffer modulation method. In this biophotonic chip, single cell is trapped optically in the cavity, and the transmission spectral shifts due to the change of surrounding buffer, without and with cell, are used to determine the cell's refractive index (RI) and size. The measurement shows that MDCK cell has an effective RI of 1.383 at a precision of 0.1%. Moreover, the measurement method with optical trapping eliminates uncertain factors and prevents cell damage. The chip is promising for label-free cell measurement and further cell analysis. ©2007 IEEE.

AB - This paper reports a single cell refractometer consists of FBG fiber-based resonant cavity by employing buffer modulation method. In this biophotonic chip, single cell is trapped optically in the cavity, and the transmission spectral shifts due to the change of surrounding buffer, without and with cell, are used to determine the cell's refractive index (RI) and size. The measurement shows that MDCK cell has an effective RI of 1.383 at a precision of 0.1%. Moreover, the measurement method with optical trapping eliminates uncertain factors and prevents cell damage. The chip is promising for label-free cell measurement and further cell analysis. ©2007 IEEE.

KW - Buffer modulation and refractive index

KW - Fiber bragg gratings

KW - Single cell measurement

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-50049084927&origin=recordpage

U2 - 10.1109/SENSOR.2007.4300264

DO - 10.1109/SENSOR.2007.4300264

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 1424408423

SN - 9781424408429

T3 - TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems

SP - 851

EP - 854

BT - TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems

T2 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07

Y2 - 10 June 2007 through 14 June 2007

ER -

Chin LK, Lim CS, Yap PH, Ng JH, Hao JZ, Takahashi S et al. Single living cell refractometry using FBG-based resonant cavity. In TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems. 2007. p. 851-854. 4300264. (TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems). doi: 10.1109/SENSOR.2007.4300264

Single living cell refractometry using FBG-based resonant cavity

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