TY - GEN
T1 - Simultaneous depth and viscoelasticity measurement of micro-structures using echo effect in a photoacoustic imaging system
AU - Zhao, Wenxiu
AU - Yu, Haibo
AU - Wen, Yangdong
AU - Wang, Xiaoduo
AU - Liu, Lianqing
AU - Li, Wen Jung
PY - 2021/12
Y1 - 2021/12
N2 - Mechanical property measurement of biological tissues is important for physiological and pathological studies. Photoacoustic (PA) methods have been a useful tool for mechanical property measurement with the advantages of optical contrast and noninvasive property. PA method uses the time information of PA signal to characterize viscoelasticity, which, however, is contradictory to depth measurement. In this work, echo signal in PA imaging system was utilized as an additional source making it possible to simultaneously measure viscoelasticity and depth. The average time and interval time of main and echo signals were used for viscoelasticity and depth measurement, respectively. Three gelatin samples with different mechanical properties at different depths were successfully distinguished by this method. The three-dimensional viscoelasticity measurement will further broaden applications in biological tissue research.
AB - Mechanical property measurement of biological tissues is important for physiological and pathological studies. Photoacoustic (PA) methods have been a useful tool for mechanical property measurement with the advantages of optical contrast and noninvasive property. PA method uses the time information of PA signal to characterize viscoelasticity, which, however, is contradictory to depth measurement. In this work, echo signal in PA imaging system was utilized as an additional source making it possible to simultaneously measure viscoelasticity and depth. The average time and interval time of main and echo signals were used for viscoelasticity and depth measurement, respectively. Three gelatin samples with different mechanical properties at different depths were successfully distinguished by this method. The three-dimensional viscoelasticity measurement will further broaden applications in biological tissue research.
UR - https://www.scopus.com/pages/publications/85128207372
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85128207372&origin=recordpage
U2 - 10.1109/ROBIO54168.2021.9739268
DO - 10.1109/ROBIO54168.2021.9739268
M3 - RGC 32 - Refereed conference paper (with host publication)
SN - 9781665405362
T3 - IEEE International Conference on Robotics and Biomimetics, ROBIO
SP - 36
EP - 41
BT - 2021 IEEE International Conference on Robotics and Biomimetics, IEEE-ROBIO 2021
PB - IEEE
T2 - 2021 IEEE International Conference on Robotics and Biomimetics (IEEE-ROBIO 2021)
Y2 - 27 December 2021 through 31 December 2021
ER -