TY - JOUR
T1 - Simulation Study of an Ultrasound Retinal Prosthesis with a Novel Contact-Lens Array for Noninvasive Retinal Stimulation
AU - Gao, Mengdi
AU - Yu, Yanyan
AU - Zhao, Huixia
AU - Li, Guofeng
AU - Jiang, Hongyang
AU - Wang, Congzhi
AU - Cai, Feiyan
AU - Chan, Leanne Lai-Hang
AU - Chiu, Bernard
AU - Qian, Wei
AU - Qiu, Weibao
AU - Zheng, Hairong
PY - 2017/9
Y1 - 2017/9
N2 - Millions of people around the world suffer from varying degrees of vision loss (including complete blindness) because of retinal degenerative diseases. Artificial retinal prosthesis, which is usually based on electrical neurostimulation, are the most advanced technology for different types of retinal degeneration. However, this technology involves placing a device into the eyeball, and such a highly invasive procedure is inevitably highly risk and expensive. Ultrasound has been demonstrated to be a promising technology for noninvasive neurostimulation, making it possible to stimulate the retina and induce action potentials similar to those elicited by light stimulation. However, the technology of ultrasound retinal stimulation still requires considerable developments before it could be applied clinically. This paper proposes a novel contact-lens array transducer for use in an ultrasound retinal prosthesis (USRP). The transducer was designed in the shape of a contact lens so as to facilitate acoustic coupling with the eye liquid. The key parameters of the ultrasound transducer were simulated, and results are presented that indicate the achievement of two-dimensional pattern generation and that the proposed contact-lens array is suitable for multiple-focus neurostimulation, and can be used in a USRP.
AB - Millions of people around the world suffer from varying degrees of vision loss (including complete blindness) because of retinal degenerative diseases. Artificial retinal prosthesis, which is usually based on electrical neurostimulation, are the most advanced technology for different types of retinal degeneration. However, this technology involves placing a device into the eyeball, and such a highly invasive procedure is inevitably highly risk and expensive. Ultrasound has been demonstrated to be a promising technology for noninvasive neurostimulation, making it possible to stimulate the retina and induce action potentials similar to those elicited by light stimulation. However, the technology of ultrasound retinal stimulation still requires considerable developments before it could be applied clinically. This paper proposes a novel contact-lens array transducer for use in an ultrasound retinal prosthesis (USRP). The transducer was designed in the shape of a contact lens so as to facilitate acoustic coupling with the eye liquid. The key parameters of the ultrasound transducer were simulated, and results are presented that indicate the achievement of two-dimensional pattern generation and that the proposed contact-lens array is suitable for multiple-focus neurostimulation, and can be used in a USRP.
KW - contact-lens shape array
KW - multiple-focus neurostimulation
KW - noninvasive stimulation
KW - Ultrasound neurostimulation
KW - ultrasound retinal prosthesis (USRP)
UR - http://www.scopus.com/inward/record.url?scp=85029577734&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85029577734&origin=recordpage
U2 - 10.1109/TNSRE.2017.2682923
DO - 10.1109/TNSRE.2017.2682923
M3 - RGC 21 - Publication in refereed journal
SN - 1534-4320
VL - 25
SP - 1605
EP - 1611
JO - IEEE Transactions on Neural Systems and Rehabilitation Engineering
JF - IEEE Transactions on Neural Systems and Rehabilitation Engineering
IS - 9
M1 - 7879335
ER -