Sicca Symptoms, Oral Health Conditions, Salivary Flow and Oral Candida in Sjögren’s Syndrome Patients

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Weini Xin
  • Katherine Chiu Man Leung
  • Edward Chin Man Lo
  • Mo Yin Mok
  • Moon Ho Leung

Related Research Unit(s)

Detail(s)

Original languageEnglish
Article number3625
Journal / PublicationInternational Journal of Environmental Research and Public Health
Volume17
Issue number10
Online published21 May 2020
Publication statusPublished - May 2020

Link(s)

Abstract

This study aimed to investigate the relationships among sicca symptoms, oral health conditions, salivary profiles and oral Candida in Sjögren’s syndrome (SS) patients. Eighty-five SS patients (mean age = 50.5) and 40 healthy non-SS individuals (mean age = 51.4) were recruited. They self-completed the Sicca Symptoms Inventory (SSI). Decayed, missing and filled surface (DMFS) scores, salivary flow rates, pH and oral Candida colonization were determined. Mean SSI summary scores of SS patients and non-SS individuals were 11.1 and 5.4 respectively (p < 0.001). The most prevalent sicca symptoms in SS patients were eye irritation (93%), dry throat or nose (88%) and need of fluid for mouth wetting (88%). SS patients had significantly lower whole salivary flow rates than the non-SS individuals. Candida strains were isolated from over 60% of SS patients but not in non-SS patients. C. albicans was the predominant species. SSI summary score was negatively correlated to salivary flow rates while SSI summary and domain scores were positively correlated to the number of filled surfaces (FS) and DMFS scores and oral Candida counts. In conclusion, SS patients had more severe sicca symptoms than non-SS individuals. SSI scores were negatively correlated to the salivary flow rates but positively correlated to caries experience and oral Candida colonization.

Research Area(s)

  • Oral Candida, Patient-reported outcomes, Sicca Symptoms Inventory, Sjögren’s syndrome

Citation Format(s)

Sicca Symptoms, Oral Health Conditions, Salivary Flow and Oral Candida in Sjögren’s Syndrome Patients. / Xin, Weini; Leung, Katherine Chiu Man; Lo, Edward Chin Man; Mok, Mo Yin; Leung, Moon Ho.

In: International Journal of Environmental Research and Public Health, Vol. 17, No. 10, 3625, 05.2020.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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