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Sensing of bacterial endotoxin in aqueous solution by supramolecular assembly of pyrene derivative

  • Lintao Zeng
  • , Jiasheng Wu
  • , Qing Dai
  • , Weimin Liu
  • , Pengfei Wang*
  • , Chun-Sing Lee*
  • *Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

N,N-Dimethyl-N-(pyrenyl-1-methyl) dodecan-1-ammonium has been designed and applied as a fluorescent probe for sensing bacterial endotoxin. Upon assembly with bacterial endotoxin (lipopolysaccharide) in aqueous solution, the probe exhibits a ratiometric and sensitive fluorescence response with a low detection limit (100 nM). Moreover, the probe shows high selectivity for bacterial endotoxin over other related biological species. © 2010 American Chemical Society.
Original languageEnglish
Pages (from-to)4014-4017
JournalOrganic Letters
Volume12
Issue number18
DOIs
Publication statusPublished - 17 Sept 2010

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