SELECTIVE FUNCTIONALIZATION OF SEMICONDUCTOR QUANTUM DOTS WITH SHORT PEPTIDES AND INTEGRINS OF CANCER CELLS FOR BIOPHOTONIC APPLICATIONS

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review

2 Scopus Citations
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Author(s)

  • B. H. BAIRAMOV
  • V. V. TOPOROV
  • F. B. BAYRAMOV
  • M. PETUKHOV
  • E. A. GLAZUNOV
  • V. LANZOV
  • Y. LI
  • D. RAMADURAI
  • M. DUTTA
  • M. A. STROSCIO
  • G. IRMER

Detail(s)

Original languageEnglish
Title of host publicationPhysics, Chemistry and Application of Nanostructures: Reviews and Short Notes: Proceedings of the International Conference, Nanomeeting-2007, Minsk, Belarus, 22-25 May 2007
EditorsV E Borisenko, V S Gurin, S V Gaponenko
Place of PublicationSingapore
PublisherWorld Scientific Publishing Co.
Pages511-515
ISBN (Electronic)9789814475709, 9789812770950
ISBN (Print)9789812705990
Publication statusPublished - May 2007
Externally publishedYes

Conference

TitleInternational Conference on Physics, Chemistry and Application of Nanostructures (NANOMEETING-2007)
PlaceBelarus
CityMinsk
Period22 - 25 May 2007

Abstract

We discuss our results on study of structural properties of the nanoscale integrated colloidal semiconductor quantum dots (SQDs) such as CdS and ZnS-capped CdSe conjugated with biomolecules such as short peptides and integrins of cancer MDA-MB- 435 cells for biomedical applications. We study chemically prepared CdS SQDs functionalized with peptides composed of the following aminoacid chains: CGGGRGDS, CGGGRVDS, CGGIKVAV, and CGGGLDV. The effective diameter of the CdS SQDs is 3 nm. The cysteine (C) aminoacid links to CdS SQDs via the thiol link, the GGG sequences of glycine (G) amino acid, provide a spacer in the amino acid chain. The RGDS, RVDS, IKAV, and LDV sequences have selective affinities to specialized transmembrane cellular structures known as integrins of neurons and MDA-MB-435 cancer cells, respectively. We also studied a role of water and other bioenvironments in stability, surface properties, dynamical and structural characteristics of these systems.

Citation Format(s)

SELECTIVE FUNCTIONALIZATION OF SEMICONDUCTOR QUANTUM DOTS WITH SHORT PEPTIDES AND INTEGRINS OF CANCER CELLS FOR BIOPHOTONIC APPLICATIONS. / BAIRAMOV, B. H.; TOPOROV, V. V.; BAYRAMOV, F. B.; PETUKHOV, M.; GLAZUNOV, E. A.; LANZOV, V.; LI, Y.; RAMADURAI, D.; SHI, P.; DUTTA, M.; STROSCIO, M. A.; IRMER, G.

Physics, Chemistry and Application of Nanostructures: Reviews and Short Notes: Proceedings of the International Conference, Nanomeeting-2007, Minsk, Belarus, 22-25 May 2007. ed. / V E Borisenko; V S Gurin; S V Gaponenko. Singapore : World Scientific Publishing Co., 2007. p. 511-515.

Research output: Chapters, Conference Papers, Creative and Literary Works (RGC: 12, 32, 41, 45)32_Refereed conference paper (with ISBN/ISSN)peer-review