Searching oligo sets of human chromosome 12 using evolutionary strategies

Yen-Yen Joe; Huan Xu; Zhao-Yang Dong; Huck-Hui Ng; Arthur Tay

doi:10.1109/CEC.2003.1299817

Searching oligo sets of human chromosome 12 using evolutionary strategies

Yen-Yen Joe
, Huan Xu
, Zhao-Yang Dong
, Huck-Hui Ng
, Arthur Tay

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

DNA microarray is a powerful tool to measure the level of a mixed population of nucleic acids at one time, which has great impact in many aspects of life sciences research. In order to distinguish nucleic acids with very similar composition by hybridization, it is necessary to design probes with high specificities, i.e. uniqueness, and also sensitivities, i.e., suitable melting temperature and no secondary structure. We make use of available biology tools to gain necessary sequence information of human chromosome 12, and combined with evolutionary strategy (ES) to find unique subsequences representing all predicted exons. The results are presented and discussed. © 2003 IEEE.

Original language	English
Title of host publication	2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings
Publisher	IEEE Computer Society
Pages	1288-1293
Volume	2
DOIs	https://doi.org/10.1109/CEC.2003.1299817
Publication status	Published - 2003
Externally published	Yes
Event	2003 Congress on Evolutionary Computation, CEC 2003 - Canberra, ACT, Australia Duration: 8 Dec 2003 → 12 Dec 2003

Publication series

Name	2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings
Volume	2

Conference

Conference	2003 Congress on Evolutionary Computation, CEC 2003
Place	Australia
City	Canberra, ACT
Period	8/12/03 → 12/12/03

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

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Joe, Y.-Y., Xu, H., Dong, Z.-Y., Ng, H.-H., & Tay, A. (2003). Searching oligo sets of human chromosome 12 using evolutionary strategies. In 2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings (Vol. 2, pp. 1288-1293). Article 1299817 (2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings; Vol. 2). IEEE Computer Society. https://doi.org/10.1109/CEC.2003.1299817

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abstract = "DNA microarray is a powerful tool to measure the level of a mixed population of nucleic acids at one time, which has great impact in many aspects of life sciences research. In order to distinguish nucleic acids with very similar composition by hybridization, it is necessary to design probes with high specificities, i.e. uniqueness, and also sensitivities, i.e., suitable melting temperature and no secondary structure. We make use of available biology tools to gain necessary sequence information of human chromosome 12, and combined with evolutionary strategy (ES) to find unique subsequences representing all predicted exons. The results are presented and discussed. {\textcopyright} 2003 IEEE.",

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Joe, Y-Y, Xu, H, Dong, Z-Y, Ng, H-H & Tay, A 2003, Searching oligo sets of human chromosome 12 using evolutionary strategies. in 2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings. vol. 2, 1299817, 2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings, vol. 2, IEEE Computer Society, pp. 1288-1293, 2003 Congress on Evolutionary Computation, CEC 2003, Canberra, ACT, Australia, 8/12/03. https://doi.org/10.1109/CEC.2003.1299817

Searching oligo sets of human chromosome 12 using evolutionary strategies. / Joe, Yen-Yen; Xu, Huan; Dong, Zhao-Yang et al.
2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings. Vol. 2 IEEE Computer Society, 2003. p. 1288-1293 1299817 (2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings; Vol. 2).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

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T1 - Searching oligo sets of human chromosome 12 using evolutionary strategies

AU - Joe, Yen-Yen

AU - Xu, Huan

AU - Dong, Zhao-Yang

AU - Ng, Huck-Hui

AU - Tay, Arthur

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2003

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N2 - DNA microarray is a powerful tool to measure the level of a mixed population of nucleic acids at one time, which has great impact in many aspects of life sciences research. In order to distinguish nucleic acids with very similar composition by hybridization, it is necessary to design probes with high specificities, i.e. uniqueness, and also sensitivities, i.e., suitable melting temperature and no secondary structure. We make use of available biology tools to gain necessary sequence information of human chromosome 12, and combined with evolutionary strategy (ES) to find unique subsequences representing all predicted exons. The results are presented and discussed. © 2003 IEEE.

AB - DNA microarray is a powerful tool to measure the level of a mixed population of nucleic acids at one time, which has great impact in many aspects of life sciences research. In order to distinguish nucleic acids with very similar composition by hybridization, it is necessary to design probes with high specificities, i.e. uniqueness, and also sensitivities, i.e., suitable melting temperature and no secondary structure. We make use of available biology tools to gain necessary sequence information of human chromosome 12, and combined with evolutionary strategy (ES) to find unique subsequences representing all predicted exons. The results are presented and discussed. © 2003 IEEE.

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T3 - 2003 Congress on Evolutionary Computation, CEC 2003 - Proceedings

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ER -

Searching oligo sets of human chromosome 12 using evolutionary strategies

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