Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications

Cangjie Yang; Xiaochen Wang; Mingfeng Wang; Keming Xu; Chenjie Xu

doi:10.1002/chem.201604741

Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications

Cangjie Yang
, Xiaochen Wang
, Mingfeng Wang^*
, Keming Xu
, Chenjie Xu

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

53 Citations (Scopus)

Abstract

Colloidal nanoparticles (NPs) containing near-infrared-fluorescent J-aggregates (JAGGs) of pyrrolopyrrole cyanines (PPcys) stabilized by amphiphilic block co-polymers were prepared in aqueous medium. JAGG formation can be tuned by means of the chemical structure of PPcys, the concentration of chromophores inside the polymeric NPs, and ultrasonication. The JAGG NPs exhibit a narrow emission band at 773 nm, a fluorescence quantum yield comparable to that of indocyanine green, and significantly enhanced photostability, which is ideal for long-term bioimaging.

Original language	English
Pages (from-to)	4310-4319
Journal	Chemistry - A European Journal
Volume	23
Issue number	18
Online published	20 Jan 2017
DOIs	https://doi.org/10.1002/chem.201604741
Publication status	Published - 28 Mar 2017
Externally published	Yes

Research Keywords

aggregation
colloids
fluorescence
imaging agents
nanoparticles

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10.1002/chem.201604741

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@article{4add4bd8a16f46ec844934ad52cf04c4,

title = "Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications",

abstract = "Colloidal nanoparticles (NPs) containing near-infrared-fluorescent J-aggregates (JAGGs) of pyrrolopyrrole cyanines (PPcys) stabilized by amphiphilic block co-polymers were prepared in aqueous medium. JAGG formation can be tuned by means of the chemical structure of PPcys, the concentration of chromophores inside the polymeric NPs, and ultrasonication. The JAGG NPs exhibit a narrow emission band at 773 nm, a fluorescence quantum yield comparable to that of indocyanine green, and significantly enhanced photostability, which is ideal for long-term bioimaging.",

keywords = "aggregation, colloids, fluorescence, imaging agents, nanoparticles",

author = "Cangjie Yang and Xiaochen Wang and Mingfeng Wang and Keming Xu and Chenjie Xu",

year = "2017",

month = mar,

day = "28",

doi = "10.1002/chem.201604741",

language = "English",

volume = "23",

pages = "4310--4319",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "John Wiley \& Sons",

number = "18",

}

Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications. / Yang, Cangjie; Wang, Xiaochen; Wang, Mingfeng et al.
In: Chemistry - A European Journal, Vol. 23, No. 18, 28.03.2017, p. 4310-4319.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media

T2 - From Spectral Tailoring to Bioimaging Applications

AU - Yang, Cangjie

AU - Wang, Xiaochen

AU - Wang, Mingfeng

AU - Xu, Keming

AU - Xu, Chenjie

PY - 2017/3/28

Y1 - 2017/3/28

N2 - Colloidal nanoparticles (NPs) containing near-infrared-fluorescent J-aggregates (JAGGs) of pyrrolopyrrole cyanines (PPcys) stabilized by amphiphilic block co-polymers were prepared in aqueous medium. JAGG formation can be tuned by means of the chemical structure of PPcys, the concentration of chromophores inside the polymeric NPs, and ultrasonication. The JAGG NPs exhibit a narrow emission band at 773 nm, a fluorescence quantum yield comparable to that of indocyanine green, and significantly enhanced photostability, which is ideal for long-term bioimaging.

AB - Colloidal nanoparticles (NPs) containing near-infrared-fluorescent J-aggregates (JAGGs) of pyrrolopyrrole cyanines (PPcys) stabilized by amphiphilic block co-polymers were prepared in aqueous medium. JAGG formation can be tuned by means of the chemical structure of PPcys, the concentration of chromophores inside the polymeric NPs, and ultrasonication. The JAGG NPs exhibit a narrow emission band at 773 nm, a fluorescence quantum yield comparable to that of indocyanine green, and significantly enhanced photostability, which is ideal for long-term bioimaging.

KW - aggregation

KW - colloids

KW - fluorescence

KW - imaging agents

KW - nanoparticles

UR - https://www.scopus.com/pages/publications/85016249687

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85016249687&origin=recordpage

U2 - 10.1002/chem.201604741

DO - 10.1002/chem.201604741

M3 - RGC 21 - Publication in refereed journal

C2 - 27918633

SN - 0947-6539

VL - 23

SP - 4310

EP - 4319

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 18

ER -

Robust Colloidal Nanoparticles of Pyrrolopyrrole Cyanine J-Aggregates with Bright Near-Infrared Fluorescence in Aqueous Media: From Spectral Tailoring to Bioimaging Applications

Abstract

Research Keywords

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