Rhoda-Electrocatalyzed Bimetallic C−H Oxygenation by Weak O-Coordination

Xuefeng Tan, Leonardo Massignan, Xiaoyan Hou, Johanna Frey, João C. A. Oliveira, Masoom Nasiha Hussain, Lutz Ackermann*

*Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

38 Citations (Scopus)

Abstract

Rhodium-electrocatalyzed arene C−H oxygenation by weakly O-coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C−H functionalization. Detailed mechanistic studies by experiment, mass spectroscopy and cyclovoltammetric analysis provided support for an unprecedented electrooxidation-induced C−H activation by a bimetallic rhodium catalysis manifold. © 2021 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH
Original languageEnglish
Pages (from-to)13264-13270
JournalAngewandte Chemie - International Edition
Volume60
Issue number24
Online published2 Mar 2021
DOIs
Publication statusPublished - 7 Jun 2021
Externally publishedYes

Research Keywords

  • cascade
  • C−H activation
  • electrochemistry
  • oxygenation
  • rhodium

Fingerprint

Dive into the research topics of 'Rhoda-Electrocatalyzed Bimetallic C−H Oxygenation by Weak O-Coordination'. Together they form a unique fingerprint.

Cite this