Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Shuzhong He
  • Hongguang Li
  • Yuk-Wang Yip
  • Chi-Tung Yeung
  • Yuen On Fung
  • Ho-Lun Yeung
  • Ga-Lai Law
  • Ka-Leung Wong
  • Chi-Sing Lee
  • Margaret B. Murphy
  • Wing-Tak Wong

Detail(s)

Original languageEnglish
Pages (from-to)5036-5039
Journal / PublicationOrganic Letters
Volume13
Issue number19
Publication statusPublished - 7 Oct 2011
Externally publishedYes

Abstract

A water-soluble europium(III) complex (1) has been synthesized and demonstrated to be a specific fluorescence probe for the paralytic shellfish toxin saxitoxin, a neurotoxin that blocks the voltage-gated sodium channels on cell membranes. Saxitoxin binds to the europium complex (K B = 6.1×10 4 M -1) and triggers a two-photon induced f-f emission enhancement by over 100% and increases the two-photon absorption crosssection from 9 to 36 GM. © 2011 American Chemical Society.

Citation Format(s)

Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin. / He, Shuzhong; Li, Hongguang; Yip, Yuk-Wang; Yeung, Chi-Tung; Fung, Yuen On; Kong, Hoi-Kuan; Yeung, Ho-Lun; Law, Ga-Lai; Wong, Ka-Leung; Lee, Chi-Sing; Lam, Michael Hon-Wah; Murphy, Margaret B.; Lam, Paul Kwan-Sing; Wong, Wing-Tak.

In: Organic Letters, Vol. 13, No. 19, 07.10.2011, p. 5036-5039.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal